L-CITRULLINE (5,5-D2) is an isotopically labeled, non-proteinogenic-free amino acid derivative of citrulline featuring the urea-bearing side chain characteristic of L-citrulline, with deuterium incorporated at the 5,5 positions (D2) for isotopic tracing. The molecule contains a free α-amino group and a free α-carboxyl group, and its side chain presents a urea functionality that can participate in hydrogen bonding and polar interactions while maintaining the same overall connectivity as unlabeled citrulline. L-CITRULLINE (5,5-D2) is used in analytical method development and isotopic labeling workflows such as LC-MS/MS quantification, amino acid profiling, and mechanistic or metabolic studies where the mass shift from the deuterium label enables discrimination from the unlabeled analyte.
CAT No: L-Iso-0163
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