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Leu-AMC HCl

Leu-AMC HCl is a fluorogenic substrate for LAP3 (leucine aminopeptidase). Upon enzyme activity, a bright blue fluorescent dye, 7-amino-4-methylcoumarin, is released.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Leu-AMC HCl(CAS 62480-44-8)

CAT No: R1916

CAS No:62480-44-8

Synonyms/Alias:62480-44-8;L-Leucine-7-amido-4-methylcoumarin hydrochloride;H-L-LEU-AMC HCL;L-Leucine 7-amido-4-methylcoumarin hydrochloride;(S)-2-amino-4-methyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)pentanamide hydrochloride;(2S)-2-amino-4-methyl-N-(4-methyl-2-oxochromen-7-yl)pentanamide;hydrochloride;L-Leucine 7-amido-4-methylcoumarin hydrochloride salt;L-Leucine-7-amido-4-methylcoumarin (hydrochloride);Pentanamide,2-amino-4-methyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohydrochloride, (2S)-;Leu-AMC;L-Leu-AMC (hydrochloride);L-Leucine-AMC.HCl;L-Leucin-7-amido-4-methylcoumarin-hydrochlorid;(2S)-2-amino-4-methyl-N-(4-methyl-2-oxo-chromen-7-yl)pentanamide Hydrochloride;MFCD00043262;L-Leu-AMC·HCl;H-L-Leu-amc hydrochloride;SCHEMBL381193;AKOS025295556;EL15997;AS-74553;HY-137844;CS-0142346;E78667;Leucine-7-amido-4-methylcoumarine hydrochloride;L-Leucine-7-amido-4-methylcoumarin hydrochloride;L-Leucine-7-amido-4-methylcouramin hydrochloride salt;(2S)-2-amino-4-methyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)pentanamide hydrochloride;(S)-2-Amino-4-methyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-pentanamide Monohydrochloride; (2S)-2-Amino-4-methyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-pentanamide Monohydrochloride;;Pentanamide,2-amino-4-methyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-,monohydrochloride,(2S)-(9ci);

Chemical Name:(2S)-2-amino-4-methyl-N-(4-methyl-2-oxochromen-7-yl)pentanamide;hydrochloride

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C16H21ClN2O3
M.W/Mr.
324.8
Sequence
One Letter Code:L
Three Letter Code:H-Leu-AMC.HCl
Appearance
White to off-white powder
Long-term Storage Conditions
Soluble in methanol
InChI
InChI=1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1
InChI Key
VCRXITKKWBOQRZ-ZOWNYOTGSA-N
Canonical SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CC(C)C)N.Cl
Isomeric SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@H](CC(C)C)N.Cl

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