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Leu-Pro-Phe-Phe-Asp

Leu-Pro-Phe-Phe-Asp blends hydrophobic, aromatic, and acidic residues that produce a balanced environment for folding studies. Proline imposes steric constraints that guide conformational sampling. The sequence serves as a substrate model for enzyme specificity research. Applications include structure-function analysis, binding studies, and synthetic method development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Leu-Pro-Phe-Phe-Asp(CAS 182912-74-9)

CAT No: R2446

CAS No:182912-74-9

Synonyms/Alias:182912-74-9;Leu-Pro-Phe-Phe-Asp;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]butanedioic acid;(PRO18,ASP21)-AMYLOID BETA-PROTEIN (17-21);LPFFD;Beta-Sheet Breaker Peptide iA|A5;Beta-Sheet Breaker Peptide iA5;DTXSID00436123;HY-P1047;FP109385;PD163358;CS-0025317;(Pro18,Asp21)-Amyloid b-Protein (17-21) trifluoroacetate salt;L-Aspartic acid,L-leucyl-L-prolyl-L-phenylalanyl-L-phenylalanyl-;(2S)-2-[(2S)-2-[(2S)-2-{[(2S)-1-[(2S)-2-AMINO-4-METHYLPENTANOYL]PYRROLIDIN-2-YL]FORMAMIDO}-3-PHENYLPROPANAMIDO]-3-PHENYLPROPANAMIDO]BUTANEDIOIC ACID;

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C33H43N5O8
M.W/Mr.
637.7
Sequence
One Letter Code:LPFFD
Three Letter Code:H-Leu-Pro-Phe-Phe-Asp-OH
InChI
InChI=1S/C33H43N5O8/c1-20(2)16-23(34)32(44)38-15-9-14-27(38)31(43)36-25(18-22-12-7-4-8-13-22)29(41)35-24(17-21-10-5-3-6-11-21)30(42)37-26(33(45)46)19-28(39)40/h3-8,10-13,20,23-27H,9,14-19,34H2,1-2H3,(H,35,41)(H,36,43)(H,37,42)(H,39,40)(H,45,46)/t23-,24-,25-,26-,27-/m0/s1
InChI Key
RALAXQOLLAQGTI-IRGGMKSGSA-N

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