[Leu5]-Enkephalin

[Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

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[Leu5]-Enkephalin(CAS 58822-25-6)

CAT No: R1123

CAS No: 58822-25-6

Synonyms/Alias: Leu-enkephalin;[Leu5]-Enkephalin;leucine enkephalin;58822-25-6;Enkephalin;Enkephalins;Enkephalin L;[Leu]enkephalin;Tyr-Gly-Gly-Phe-Leu;Leucyl-enkephalin;Leucine-enkephalin;ENKEPHALIN, LEUCINE;H-Tyr-Gly-Gly-Phe-Leu-OH;[5-Leucine]Enkephalin;Leu5-Enkephalin;Tyr-Gly-Gly-Phe-Leu-OH;Leucine- enkephalin;[Leu 5]enkephalin;(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid;CHEMBL8234;L-Tyr-Gly-Gly-L-Phe-L-Leu;CHEBI:89656;L-Tyrosylglycylglycyl-L-phenylalanyl-L-leucine;RI01R707R6;N-(N-(N-(N-L-Tyrosylglycyl)glycyl)-L-phenylalanyl)-L-leucine;Leu-Enkephalin Acetate;59141-40-1;Leu-enkephalin;Leucine enkephalin;Leucyl-enkephalin;L-Leucine, N-(N-(N-(N-L-tyrosylglycyl)glycyl)-L-phenylalanyl)-;(2S)-2-[(2S)-2-(2-{2-[(2S)-2-AMINO-3-(4-HYDROXYPHENYL)PROPANAMIDO]ACETAMIDO}ACETAMIDO)-3-PHENYLPROPANAMIDO]-4-METHYLPENTANOIC ACID;Dynorphin-(1-5);UNII-RI01R707R6;TyrGlyGlyPheLeu;CCRIS 6338;NSC350588;14-18-6;NSC-350588;LeuENK;EINECS 261-457-1;Leu-ENK;MFCD00076406;[Leu(5)]enkephalin;ICI 114740;NSC 350588;[Leu(5)]-enkephalin;PENTAPEPTIDE-5;L-ENK;SM-PEPTIDE-1;SH-PENTAPEPTIDE-5;Y-G-G-F-L;SCHEMBL631959;CHEMBL218452;DTXSID00905127;HY-P0288;BDBM50001465;BDBM50128075;AKOS024456832;FL73373;ICI-114740;NCGC00167126-01;DA-64928;MS-30127;NS00056490;Leu-Enkephalin (H-L-Tyr-Gly-Gly-L-Phe-L-Leu-OH);Q6533903;Tyr-Gly-Pro-Phe-Leu-Arg-Arg-Ile-Arg-Arg-Lys-NH2;L-LEUCINE, L-TYROSYLGLYCYLGLYCYL-L-PHENYLALANYL-;L-Leucine-enkephalin acetate;Dynorphin A (1-5);H-Tyr-Gly-Gly-Phe-Leu-OH acetate;([Leu]-enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid;(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino];(2S,5S,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-2-isobutyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecan-1-oic acid;(enkephalin)2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid;(S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid;2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-1-oxo-3-phenyl-propylamino]-4-methyl-pentanoic acid;2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid;2-[1-[1-amino-2-(4-hydroxyphenyl)-(1S)-ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenyl-(1S)-ethylcarboxamido]-4-methyl-(2S)-pentanoic acid;2-[2-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid(Enkephalin);2-{1-[1-amino-2-(4-hydroxyphenyl)ethylcarboxamidomethylcarboxamidomethylcarboxamido]-2-phenylethylcarboxamido}-4-methylpentanoic acid;

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Specification Technical Data Publications Customer reviews and Q&A
M.F/FormulaC28H37N5O7
M.W/Mr.555.6
SequenceOne Letter Code:YGGFL
Three Letter Code:H-Tyr-Gly-Gly-Phe-Leu-OH
Purity≥95%
Length5
Long-term Storage ConditionsSoluble to 1 mg/ml in water
Shipping ConditionShipped at room temperature
InChIInChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1
InChI KeyURLZCHNOLZSCCA-VABKMULXSA-N
Canonical SMILES[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(O)=O

1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

2. The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

3. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

4. Odorant binding protein based biomimetic sensors for detection of alcohols associated with Salmonella contamination in packaged beef

5. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

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