Lysipressin

Name: Lysipressin
Brand: Creative Peptides
SKU: 10-101-23
Availability: MadeToOrder

Lysipressin is a pressor peptide isolated from marsupials and pigs that binds to VP receptors, which are analogous to human Vasopressin 2 (V2) receptors. Lysipressin induces contractions in smooth muscle and potentiates effects of gastric lesioning in animal models.

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CAT No: 10-101-23

CAS No: 50-57-7

Synonyms/Alias: LYPRESSIN;Lysipressin;Lysine vasopressin;50-57-7;Syntopressin;8-L-Lysinevasopressin;Postacton;Diapid;Lysine pitressin;Lipresina;Lypressine;Vasopressin, 8-L-lysine-;Vasopressin pig;L-Lysine vasopressin;Vasopressin-8-lysine;Vasopressin, 8-L-lysine;[Lys8]-Vasopressin;DTXSID8048575;(8-Lysine)vasopressin;Vasopressin (lysine form);8-L-Lysine vasopressin;50-57-7 (free base);7CZF3L922Y;DTXCID8028501;(Lys8)-Vasopressin;L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1->6)-disulfide;[8-Lysine]vasopressin;Lysine-vasopressin;(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide;LVP;Lipressina;Lypressinum;Lysopressin;Lysylvasopressin;Lys Vasopressin;Lysyl Vasopressin;CAS-50-57-7;Vasopressin, Lysyl;(S)-N-((S)-6-amino-1-((2-amino-2-oxoethyl)amino)-1-oxohexan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamide;L-8;Vasopressin, Lysine;Lipressina [DCIT];8 Lysine Vasopressin;8-Lysine Vasopressin;Vasopressin, 8-Lysine;Lipresina [INN-Spanish];Lypressine [INN-French];Lypressinum [INN-Latin];UNII-7CZF3L922Y;Lysipressin?;3-(Phenylalanine)-8-lysine oxytocin;L-lysinamide,;Lysine-ADH;Lypressin [USAN:USP:INN:BAN];NCGC00181743-01;NCGC00181743-02;EINECS 200-050-5;MFCD00076754;BRN 4648365;[Lys8]AVP;LYPRESSIN (MART.);LYPRESSIN (USP-RS);SCHEMBL33287;GTPL2172;CHEMBL1200690;LYPRESSIN (USP IMPURITY);CHEBI:94802;H01BA03;Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2, cyclic 1-6 disulfide;HY-P0004;Tox21_112902;Tox21_113427;AKOS030529559;CCG-270620;CS-5838;DB14642;FL38924;NS00032082;Oxytocin, 3-(L-phenylalanine)-8-L-lysine-;Vasopressin, 8-L-lysine- (7CI,8CI,9CI);C75370;l]carbonyl]-L-prolyl-N-(2-amino-2-oxoethyl)-;BRD-K93331255-001-01-2;BRD-K93331255-001-02-0;Q27082434;1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide;Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2[Disulfide Bridge: 1-6];(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide;(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide;1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-y;19-amino-4-[2-[[5-amino-1-[(carbamoylmethyl)carbamoyl]pentyl]carbamoyl]-1-pyrrolidinylcarbonyl]-13-benzyl-7-(carbamoylmethyl)-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo- (6CI);200-050-5;Glycinamide, L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1>6)-disulfide;L 8;L-CYSTEINYL-L-TYROSYL-L-PHENYLALANYL-L-GLUTAMINYL-L-ASPARAGINYL-L-CYSTEINYL-L-PROLYL-L-LYSYLGLYCINAMIDE CYCLIC (1->6)-DISULPHIDE;L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1-6)-disulfide;

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M.F/Formula	C46H65N13O12S2
M.W/Mr.	1056.2
Sequence	One Letter Code:CYFQNCPKG Three Letter Code:H-Cys(1)-Tyr-Phe-Gln-Asn-Cys(1)-Pro-Lys-Gly-NH2
Labeling Target	Vasopressin receptor
Application	Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels, It is used to treat bleeding esophageal varices.
Appearance	Solid powder
Purity	>98% (or refer to the Certificate of Analysis)
Biological Activity	Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families. Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase.
Areas of Interest	Cardiovascular System & Diseases Pituitary & Hypothalamic Hormones

Source#	Synthetic
Long-term Storage Conditions	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions	Dry, dark and at 0 - 4 °C
Solubility	-20 °C
InChI	InChI=1S/C46H65N13O12S2/c47-17-5-4-9-29(40(65)52-22-38(51)63)54-45(70)35-10-6-18-59(35)46(71)34-24-73-72-23-28(48)39(64)55-31(20-26-11-13-27(60)14-12-26)43(68)56-32(19-25-7-2-1-3-8-25)42(67)53-30(15-16-36(49)61)41(66)57-33(21-37(50)62)44(69)58-34/h1-3,7-8,11-14,28-35,60H,4-6,9-10,15-24,47-48H2,(H2,49,61)(H2,50,62)(H2,51,63)(H,52,65)(H,53,67)(H,54,70)(H,55,64)(H,56,68)(H,57,66)(H,58,69)/t28-,29-,30-,31-,32-,33-,34-,35-/m0/s1
InChI Key	BJFIDCADFRDPIO-DZCXQCEKSA-N
BoilingPoint	1610.4±65.0 °C at 760 mmHg
ShelfLife	>2 years if stored properly
References	The neurohypophyseal hormones of the hippopotamus (Hippopotamus amphibius) and collared peccary (Tayassu angulatus) were isolated by molecular sieving and preparative high-pressure liquid chromatography (HPLC). Oxytocin and arginine vasopressin have been identified by their amino acid compositions and their retention times in HPLC. Lysipressin (lysine vasopressin) was not detected in posterior pituitaries of two hippopotami and nine peccaries (less than 2% of arginine vasopressin in molar ratios). Among the suborder Suiformes of Artiodactyla, the families Hippopotamidae and Tayassuidae do not seem to possess lysipressin, in contrast to the family Suidae in which the pig has lysipressin in place of arginine vasopressin. Rouille, Y., Chauvet, M. T., Chauvet, J., Acher, R., & Hadley, M. E. (1988). The distribution of lysine vasopressin (lysipressin) in placental mammals: a reinvestigation of the Hippopotamidae (Hippopotamus amphibius) and Tayassuidae (Tayassu angulatus) families. General and comparative endocrinology, 71(3), 475-483.
Melting Point	N/A

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