Lysipressin is a pressor peptide isolated from marsupials and pigs that binds to VP receptors, which are analogous to human Vasopressin 2 (V2) receptors. Lysipressin induces contractions in smooth muscle and potentiates effects of gastric lesioning in animal models.
CAT No: 10-101-23
CAS No:50-57-7
Synonyms/Alias:LYPRESSIN;Lysipressin;Lysine vasopressin;50-57-7;Syntopressin;8-L-Lysinevasopressin;Postacton;Diapid;Lysine pitressin;Lipresina;Lypressine;Vasopressin, 8-L-lysine-;Vasopressin pig;L-Lysine vasopressin;Vasopressin-8-lysine;Vasopressin, 8-L-lysine;[Lys8]-Vasopressin;DTXSID8048575;(8-Lysine)vasopressin;Vasopressin (lysine form);8-L-Lysine vasopressin;50-57-7 (free base);7CZF3L922Y;DTXCID8028501;(Lys8)-Vasopressin;L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1->6)-disulfide;[8-Lysine]vasopressin;Lysine-vasopressin;(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide;LVP;Lipressina;Lypressinum;Lysopressin;Lysylvasopressin;Lys Vasopressin;Lysyl Vasopressin;CAS-50-57-7;Vasopressin, Lysyl;(S)-N-((S)-6-amino-1-((2-amino-2-oxoethyl)amino)-1-oxohexan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamide;L-8;Vasopressin, Lysine;Lipressina [DCIT];8 Lysine Vasopressin;8-Lysine Vasopressin;Vasopressin, 8-Lysine;Lipresina [INN-Spanish];Lypressine [INN-French];Lypressinum [INN-Latin];UNII-7CZF3L922Y;Lysipressin?;3-(Phenylalanine)-8-lysine oxytocin;L-lysinamide,;Lysine-ADH;Lypressin [USAN:USP:INN:BAN];NCGC00181743-01;NCGC00181743-02;EINECS 200-050-5;MFCD00076754;BRN 4648365;[Lys8]AVP;LYPRESSIN (MART.);LYPRESSIN (USP-RS);SCHEMBL33287;GTPL2172;CHEMBL1200690;LYPRESSIN (USP IMPURITY);CHEBI:94802;H01BA03;Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2, cyclic 1-6 disulfide;HY-P0004;Tox21_112902;Tox21_113427;AKOS030529559;CCG-270620;CS-5838;DB14642;FL38924;NS00032082;Oxytocin, 3-(L-phenylalanine)-8-L-lysine-;Vasopressin, 8-L-lysine- (7CI,8CI,9CI);C75370;l]carbonyl]-L-prolyl-N-(2-amino-2-oxoethyl)-;BRD-K93331255-001-01-2;BRD-K93331255-001-02-0;Q27082434;1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide;Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2[Disulfide Bridge: 1-6];(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide;(2S)-N-[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]-1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentazacycloeicos-4-yl]-oxomethyl]-2-pyrrolidinecarboxamide;1-[[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-y;19-amino-4-[2-[[5-amino-1-[(carbamoylmethyl)carbamoyl]pentyl]carbamoyl]-1-pyrrolidinylcarbonyl]-13-benzyl-7-(carbamoylmethyl)-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo- (6CI);200-050-5;Glycinamide, L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-, cyclic (1>6)-disulfide;L 8;L-CYSTEINYL-L-TYROSYL-L-PHENYLALANYL-L-GLUTAMINYL-L-ASPARAGINYL-L-CYSTEINYL-L-PROLYL-L-LYSYLGLYCINAMIDE CYCLIC (1->6)-DISULPHIDE;L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysylglycinamide cyclic (1-6)-disulfide;
The neurohypophyseal hormones of the hippopotamus (Hippopotamus amphibius) and collared peccary (Tayassu angulatus) were isolated by molecular sieving and preparative high-pressure liquid chromatography (HPLC). Oxytocin and arginine vasopressin have been identified by their amino acid compositions and their retention times in HPLC. Lysipressin (lysine vasopressin) was not detected in posterior pituitaries of two hippopotami and nine peccaries (less than 2% of arginine vasopressin in molar ratios). Among the suborder Suiformes of Artiodactyla, the families Hippopotamidae and Tayassuidae do not seem to possess lysipressin, in contrast to the family Suidae in which the pig has lysipressin in place of arginine vasopressin.
Rouille, Y., Chauvet, M. T., Chauvet, J., Acher, R., & Hadley, M. E. (1988). The distribution of lysine vasopressin (lysipressin) in placental mammals: a reinvestigation of the Hippopotamidae (Hippopotamus amphibius) and Tayassuidae (Tayassu angulatus) families. General and comparative endocrinology, 71(3), 475-483.
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