Melittin

Name: Melittin
Brand: Creative Peptides
SKU: R1513
Availability: MadeToOrder

Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: R1513

CAS No: 20449-79-0

Synonyms/Alias: Melittin;20449-79-0;Honeybee melittin;Forapine;Bee venom melittin;Forapin;Melittin (honeybee);Melitten;GIGAVLKVLTTGLPALISWIKRKRQQ-NH2;MFCD00076868;CHEBI:6736;Melittin I;Melittin TFA;Melittin (major);Melittin (apis cerana);UNII-24VT8NVE75;Melittin?;L-Glutamamide, glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-Leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-;Melittin, 70%;Melittin - 95%;BEE VENOM POWDER;24VT8NVE75;CHEMBL412927;DTXSID001046261;EX-A7430;AKOS024456456;FM10065;Melittin, >=97% (HPLC), synthetic;RS-2008;NCGC00167171-01;AC-32561;DA-75406;XM176021;A12242;Melittin (GIGAVLKVLTTGLPALISWIKRKRQQ-amide);Melittin from honey bee venom, >=65% (HPLC);Melittin from honey bee venom, >=85% (HPLC);G-I-G-A-V-L-K-V-L-T-T-G-L-P-A-L-I-S-W-I-K-R-K-R-Q-Q-NH2;Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2;Gly-L-Ile-Gly-L-Ala-L-Val-L-Leu-L-Lys-L-Val-L-Leu-L-Thr-L-Thr-Gly-L-Leu-L-Pro-L-Ala-L-Leu-L-Ile-L-Ser-L-Trp-L-Ile-L-Lys-L-Arg-L-Lys-L-Arg-L-Gln-L-Gln-NH2;glycyl-L-isoleucylglycyl-L-alanyl-L-valyl-L-leucyl-L-lysyl-L-valyl-L-leucyl-L-threonyl-L-threonylglycyl-L-leucyl-L-prolyl-L-alanyl-L-leucyl-L-isoleucyl-L-seryl-L-tryptophyl-L-isoleucyl-L-lysyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-L-glutamamide;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C131H229N39O31
M.W/Mr.	2846.5
Sequence	One Letter Code:GIGAVLKVLTTGLPALISWIKRKRQQ Three Letter Code:H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2
Biological Activity	Inhibits Gs and stimulates Gi activity. Inhibits protein kinase C and cAMP-dependent protein kinases. Na+/K+ ATPase inhibitor.

Long-term Storage Conditions	Soluble to 1 mg/ml in water
Shipping Condition	Room temperature in continental US; may vary elsewhere.
InChI	InChI=1S/C131H229N39O31/c1-23-71(16)102(163-97(176)60-135)122(194)146-62-98(177)148-74(19)109(181)164-100(69(12)13)124(196)160-88(55-65(4)5)116(188)155-84(41-30-33-51-134)115(187)165-101(70(14)15)125(197)161-90(57-67(8)9)118(190)168-106(77(22)173)128(200)169-105(76(21)172)123(195)147-63-99(178)150-92(58-68(10)11)129(201)170-54-36-44-94(170)121(193)149-75(20)108(180)158-89(56-66(6)7)117(189)166-104(73(18)25-3)127(199)162-93(64-171)120(192)159-91(59-78-61-145-80-38-27-26-37-79(78)80)119(191)167-103(72(17)24-2)126(198)157-83(40-29-32-50-133)111(183)154-85(42-34-52-143-130(139)140)112(184)152-82(39-28-31-49-132)110(182)153-86(43-35-53-144-131(141)142)113(185)156-87(46-48-96(137)175)114(186)151-81(107(138)179)45-47-95(136)174/h26-27,37-38,61,65-77,81-94,100-106,145,171-173H,23-25,28-36,39-60,62-64,132-135H2,1-22H3,(H2,136,174)(H2,137,175)(H2,138,179)(H,146,194)(H,147,195)(H,148,177)(H,149,193)(H,150,178)(H,151,186)(H,152,184)(H,153,182)(H,154,183)(H,155,188)(H,156,185)(H,157,198)(H,158,180)(H,159,192)(H,160,196)(H,161,197)(H,162,199)(H,163,176)(H,164,181)(H,165,187)(H,166,189)(H,167,191)(H,168,190)(H,169,200)(H4,139,140,143)(H4,141,142,144)/t71-,72-,73-,74-,75-,76+,77+,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,100-,101-,102-,103-,104-,105-,106-/m0/s1
InChI Key	VDXZNPDIRNWWCW-JFTDCZMZSA-N

1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

2. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry

3. High fat diet and GLP-1 drugs induce pancreatic injury in mice

4. Myotropic activity of allatostatins in tenebrionid beetles

5. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

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