N-Acetyl [(pCl)DPhe1,2,DTrp3,DArg6,DAla10]-LH-RH

Name: N-Acetyl [(pCl)DPhe1,2,DTrp3,DArg6,DAla10]-LH-RH
Brand: Creative Peptides
SKU: L1622
Availability: MadeToOrder

N-Acetyl [(pCl)DPhe1,2,DTrp3,DArg6,DAla10]-LH-RH is a heavily modified LH-RH analog featuring multiple noncanonical residues. Its sequence supports studies of conformation, aromatic packing, and charge distribution. Researchers employ it to analyze ligand–receptor interaction surfaces. The peptide aids advanced design of stabilized decapeptide scaffolds.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: L1622

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

1454.6

Sequence

Ac-(pCl)DPhe-(pCl)DPhe-DTrp-Ser-Tyr-DArg-Leu-Arg-Pro-DAla-NH2

References

D. Coy et al., Science, 218, 160 (1982)

1. The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

2. High fat diet and GLP-1 drugs induce pancreatic injury in mice

3. Cationic cell-penetrating peptides are potent furin inhibitors

4. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

5. Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics

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