N-CBZ-Phe-Arg-AMC

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes.

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CAT No: R1529

CAS No: 65147-22-0

Synonyms/Alias: Z-Phe-Arg-Amc HCl;65147-22-0;70382-26-2;Z-Phe-Arg-Amc Hydrochloride;Benzyl ((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate hydrochloride;Z-Phe-Arg-AMC.HCl;MFCD00077030;benzyl N-[1-[[5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate;Z-Phe-Arg 7-amido-4-methylcoumarin hydrochloride;Purity Limit? 99% (TLC);SCHEMBL1723683;FP47305;AS-87695;G77867;7-(Nalpha -carbobenzoxy-L-phenylalanyl-L-arginyl)amino-4-methylcoumarin hydrochloric acid salt;benzyl (S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-1-oxo-3-phenylpropan-2-ylcarbamate hydrochloride;benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate;hydrochloride;Benzyl((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)carbamatehydrochloride;L-Argininamide,N-[(phenylmethoxy)carbonyl]-L-phenylalanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-;

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Specification Technical Data Publications Customer reviews and Q&A
M.F/FormulaC33H37ClN6O6
M.W/Mr.649.1
SequenceOne Letter Code:FR
Three Letter Code:Cbz-Phe-Arg-AMC.HCl
InChIInChI=1S/C33H36N6O6.ClH/c1-21-17-29(40)45-28-19-24(14-15-25(21)28)37-30(41)26(13-8-16-36-32(34)35)38-31(42)27(18-22-9-4-2-5-10-22)39-33(43)44-20-23-11-6-3-7-12-23;/h2-7,9-12,14-15,17,19,26-27H,8,13,16,18,20H2,1H3,(H,37,41)(H,38,42)(H,39,43)(H4,34,35,36);1H/t26-,27-;/m0./s1
InChI KeyNXIWJKWURGALDP-WMXJXTQLSA-N

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5. An Isolated TCR αβ Restricted by HLA-A* 02: 01/CT37 Peptide Redirecting CD8+ T Cells to Kill and Secrete IFN-γ in Response to Lung Adenocarcinoma Cell Lines

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