N-Fmoc-N-(2-fluorobenzyl)-glycine

N-Fmoc-N-(2-fluorobenzyl)-glycine incorporates a fluorinated aromatic substituent that alters hydrophobicity and steric environment. Researchers use it to probe fluorine-driven electronic effects, conformational tuning, and side-chain interactions. Its Fmoc protection supports seamless integration into synthetic peptides. The residue enriches structural diversity in engineered sequences.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

N-Fmoc-N-(2-fluorobenzyl)-glycine(CAS 2385070-08-4)

CAT No: R2152

CAS No:2385070-08-4

Synonyms/Alias:N-Fmoc-N-(2-fluorobenzyl)-glycine;2385070-08-4;{[(9H-fluoren-9-ylmethoxy)carbonyl][(2-fluorophenyl)methyl]amino}acetic acid;F81199;2-[9H-fluoren-9-ylmethoxycarbonyl-[(2-fluorophenyl)methyl]amino]acetic acid;

Custom Peptide Synthesis

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C24H20FNO4

M.W/Mr.

405.4

Sequence

One Letter Code:G
Three Letter Code:Fmoc-N(Bn(2-F))Gly-OH

InChI

InChI=1S/C24H20FNO4/c25-22-12-6-1-7-16(22)13-26(14-23(27)28)24(29)30-15-21-19-10-4-2-8-17(19)18-9-3-5-11-20(18)21/h1-12,21H,13-15H2,(H,27,28)

InChI Key

BRVAIIZVRBIKOT-UHFFFAOYSA-N

1. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

3. Proinsulin C-peptide and insulin: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling

4. Immune responses to peptides containing homocitrulline or citrulline in the DR4-transgenic mouse model of rheumatoid arthritis

5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes

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