N-Fmoc-N-(2-fluorobenzyl)-glycine

N-Fmoc-N-(2-fluorobenzyl)-glycine incorporates a fluorinated aromatic substituent that alters hydrophobicity and steric environment. Researchers use it to probe fluorine-driven electronic effects, conformational tuning, and side-chain interactions. Its Fmoc protection supports seamless integration into synthetic peptides. The residue enriches structural diversity in engineered sequences.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

N-Fmoc-N-(2-fluorobenzyl)-glycine(CAS 2385070-08-4)

CAT No: R2152

CAS No:2385070-08-4

Synonyms/Alias:N-Fmoc-N-(2-fluorobenzyl)-glycine;2385070-08-4;{[(9H-fluoren-9-ylmethoxy)carbonyl][(2-fluorophenyl)methyl]amino}acetic acid;F81199;2-[9H-fluoren-9-ylmethoxycarbonyl-[(2-fluorophenyl)methyl]amino]acetic acid;

Custom Peptide Synthesis

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C24H20FNO4

M.W/Mr.

405.4

Sequence

One Letter Code:G
Three Letter Code:Fmoc-N(Bn(2-F))Gly-OH

InChI

InChI=1S/C24H20FNO4/c25-22-12-6-1-7-16(22)13-26(14-23(27)28)24(29)30-15-21-19-10-4-2-8-17(19)18-9-3-5-11-20(18)21/h1-12,21H,13-15H2,(H,27,28)

InChI Key

BRVAIIZVRBIKOT-UHFFFAOYSA-N

1. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

2. Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

3. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

4. Proinsulin C-peptide and insulin: Limited pattern similarities of interest in inter-peptide interactions but no C-peptide effect on insulin and IGF-1 receptor signaling

5. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

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