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N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide

N-Methoxysuccinyl-Ala-Ala-Pro-Val p-Nitroanilide incorporates a protected substrate motif with a p-nitroanilide reporter for detecting serine protease activity. Proline imposes a turn-like constraint that modulates recognition. Researchers quantify cleavage via chromogenic release. Applications include protease-characterization studies, inhibitor testing, and kinetic method development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide(CAS 70967-90-7)

CAT No: PI-027

CAS No:70967-90-7

Synonyms/Alias:70967-90-7;MeOSuc-AAPV-PNA;MeOSuc-Ala-Ala-Pro-Val-PNA;MeOSuc-AAPV-pNA, Chromogenic Substrate;N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide;MeOSuc-Ala-Ala-Pro-Val-pNA;;MFCD00077137;Meo-Suc-Ala-Ala-Pro-Val-Paranitroanilide;VLVGCNNWNUERRZ-OSAZLGQLSA-N;HY-P2685;AKOS037643618;AKOS040756389;AS-17783;DA-55341;FM110732;methyl 3-{[(1S)-1-{[(2S)-1-[(2S)-2-{[(1S)-2-methyl-1-[(4-nitrophenyl)carbamoyl]propyl]carbamoyl}pyrrolidin-1-yl]-1-oxopropan-2-yl]carbamoyl}ethyl]carbamoyl}propanoate;CS-0139184;G77869;N-methoxysuccinyl-ala-ala-pro-val-p-nitroanilide;Elastase Substrate I, Colorimetric - CAS 70967-90-7;Methoxysuccinyl-Ala-Ala-Pro-Val-p-nitroanilide - CAS 70967-90-7;N-Methoxysuccinyl-Ala-Ala-Pro-Val p-nitroanilide, elastase substrate;methyl 4-((S)-1-((S)-1-((S)-2-((S)-3-methyl-1-(4-nitrophenylamino)-1-oxobutan-2-ylcarbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-ylamino)-1-oxopropan-2-ylamino)-4-oxobutanoate;

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M.F/Formula
C27H38N6O9
M.W/Mr.
590.6
Sequence
One Letter Code:AAPV
Three Letter Code:MeOSuc-Ala-Ala-Pro-Val-pNA
InChI
InChI=1S/C27H38N6O9/c1-15(2)23(26(38)30-18-8-10-19(11-9-18)33(40)41)31-25(37)20-7-6-14-32(20)27(39)17(4)29-24(36)16(3)28-21(34)12-13-22(35)42-5/h8-11,15-17,20,23H,6-7,12-14H2,1-5H3,(H,28,34)(H,29,36)(H,30,38)(H,31,37)/t16-,17-,20-,23-/m0/s1
InChI Key
VLVGCNNWNUERRZ-OSAZLGQLSA-N

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