N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin. Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity.
CAT No: R1907
CAS No: 88793-79-7
Synonyms/Alias: 88793-79-7;N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt;N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt;acetic acid;(2S)-N-[(2S)-6-amino-1-(4-nitroanilino)-1-oxohexan-2-yl]-1-[2-[(4-methylphenyl)sulfonylamino]acetyl]pyrrolidine-2-carboxamide;N-p-Tosyl-Gly-Pro-Lys-pNA (acetate);Tos-GPK-pNA;Tos-Gly-Pro-Lys-pNA acetate;MFCD00057232;SCHEMBL16234756;KPGSNEYSJPIZCW-SJEIDVEUSA-N;AKOS040755132;HY-137798;CS-0142060;N-p-tosyl-gly-pro-lysp-nitroanilideacetatesalt;N-(p-tosyl)-gly-pro-lys-4 nitroanilide acetate salt;N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt, plasmin substrate;(S)-N-((S)-6-amino-1-(4-nitrophenylamino)-1-oxohexan-2-yl)-1-(2-(4-methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxamide acetate;
Chemical Name: N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate
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M.F/Formula | C28H38N6O9S |
M.W/Mr. | 634.7 |
Sequence | One Letter Code:GPK Three Letter Code:Tos-Gly-Pro-Lys-pNA.CH3CO2H |
Long-term Storage Conditions | Ethanol: 50 mg/ml |
Shipping Condition | Room Temperature in continental US; may vary elsewhere. |
InChI | InChI=1S/C26H34N6O7S.C2H4O2/c1-18-7-13-21(14-8-18)40(38,39)28-17-24(33)31-16-4-6-23(31)26(35)30-22(5-2-3-15-27)25(34)29-19-9-11-20(12-10-19)32(36)37;1-2(3)4/h7-14,22-23,28H,2-6,15-17,27H2,1H3,(H,29,34)(H,30,35);1H3,(H,3,4)/t22-,23-;/m0./s1 |
InChI Key | KPGSNEYSJPIZCW-SJEIDVEUSA-N |
Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCCC2C(=O)NC(CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O |
Isomeric SMILES | CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O |
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