N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt

N-p-Tosyl-Gly-Pro-Lys-pNA is a colorimetric substrate for plasmin. Plasmin binds and hydrolyzes N-p-tosyl-Gly-Pro-Lys-pNA to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasmin activity.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt(CAS 88793-79-7)

CAT No: R1907

CAS No:88793-79-7

Synonyms/Alias:88793-79-7;N-p-Tosyl-Gly-Pro-Lys p-nitroanilide acetate salt;N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt;acetic acid;(2S)-N-[(2S)-6-amino-1-(4-nitroanilino)-1-oxohexan-2-yl]-1-[2-[(4-methylphenyl)sulfonylamino]acetyl]pyrrolidine-2-carboxamide;N-p-Tosyl-Gly-Pro-Lys-pNA (acetate);Tos-GPK-pNA;Tos-Gly-Pro-Lys-pNA acetate;MFCD00057232;SCHEMBL16234756;KPGSNEYSJPIZCW-SJEIDVEUSA-N;AKOS040755132;HY-137798;CS-0142060;N-p-tosyl-gly-pro-lysp-nitroanilideacetatesalt;N-(p-tosyl)-gly-pro-lys-4 nitroanilide acetate salt;N-(p-Tosyl)-Gly-Pro-Lys 4-nitroanilide acetate salt, plasmin substrate;(S)-N-((S)-6-amino-1-(4-nitrophenylamino)-1-oxohexan-2-yl)-1-(2-(4-methylphenylsulfonamido)acetyl)pyrrolidine-2-carboxamide acetate;

Chemical Name:N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-lysinamide, monoacetate

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cGMP Peptide
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  • Drug master files (DMF) filing
M.F/Formula
C28H38N6O9S
M.W/Mr.
634.7
Sequence
One Letter Code:GPK
Three Letter Code:Tos-Gly-Pro-Lys-pNA.CH3CO2H
Long-term Storage Conditions
Ethanol: 50 mg/ml
Shipping Condition
Room Temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C26H34N6O7S.C2H4O2/c1-18-7-13-21(14-8-18)40(38,39)28-17-24(33)31-16-4-6-23(31)26(35)30-22(5-2-3-15-27)25(34)29-19-9-11-20(12-10-19)32(36)37;1-2(3)4/h7-14,22-23,28H,2-6,15-17,27H2,1H3,(H,29,34)(H,30,35);1H3,(H,3,4)/t22-,23-;/m0./s1
InChI Key
KPGSNEYSJPIZCW-SJEIDVEUSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCCC2C(=O)NC(CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O
Isomeric SMILES
CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCCCN)C(=O)NC3=CC=C(C=C3)[N+](=O)[O-].CC(=O)O

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