N-ω-tosyl-D-arginine is a D-configured arginine derivative in which the ω-amino group of the arginine side chain is substituted with a tosyl (p-toluenesulfonyl) protecting group, while the α-amino and α-carboxyl groups remain present as the free functional termini of the amino acid framework. The molecule therefore bears an α-carboxylic acid and an α-amino group for further coupling chemistry, and its guanidinium-bearing side chain is structurally modified by N-ω tosylation that alters hydrogen-bonding and reduces side-chain nucleophilicity relative to unprotected arginine. In synthetic and biochemical workflows, this protected arginine analogue is used as a substrate or building block for peptide-related assembly and for studying arginine-dependent processes under conditions where controlled side-chain reactivity is required.
CAT No: CP00247
CAS No:97233-92-6
Synonyms/Alias:H-D-Arg(Tos)-OH;97233-92-6;C13H20N4O4S;AC1OLR95;CTK3I6523;ACT10963;ZINC2560668;KM3439;(2R)-2-amino-5-[[amino-[(4-methylphenyl)sulfonylamino]methylidene]amino]pentanoicAcid;X5761;Q-101664;D-Ornithine,N5-[imino[[(4-methylphenyl)sulfonyl]amino]methyl]-
4. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
5. Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More