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Nociceptin (1-13), amide

Nociceptin (1-13), amide is a potent ORL1 (OP4) receptor agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Nociceptin (1-13), amide(CAS 178064-02-3)

CAT No: R1563

CAS No:178064-02-3

Synonyms/Alias:178064-02-3;N/OFQ-(1-13)-NH2;nociceptin(1-13)NH2;CHEMBL384755;Nociceptin (1-13), amide;Nociceptin (1-13) amide trifluoroacetate salt;OFQ/N;FGGFTGARKSARK;nociceptin (1-13) amide;orphanin FQ(1-13)NH2;Demethyl-AMPA;nociceptin/orphanin FQ(1-13)NH2;Nociceptin Orphanin FQ..1-13..-NH..2..;H-FGGFTGARKSARK-NH2;GTPL1682;BDBM85822;N/OFQ(1-13)NH2;NC(1-13)NH2;BDBM50106479;OFQ/N (1-11);AKOS024456547;NCGC00167157-01;DA-56231;FN109170;Q27087982;Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-NH2;H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-NH2; H-FGGFTGARKSARK-NH2;(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-phenylpropanamido]acetamido}acetamido)-3-phenylpropanamido]-3-hydroxybutanamido]acetamido}propanamido]-5-carbamimidamidopentanamido]hexanamido]-3-hydroxypropanamido]propanamido]-5-carbamimidamidopentanamido]hexanamide;

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C61H100N22O15
M.W/Mr.
1381.6
Sequence
One Letter Code:FGGFTGARKSARK
Three Letter Code:H-Phe-Gly-Gly-Phe-Thr-Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-NH2
Source#
Synthetic
InChI
InChI=1S/C61H100N22O15/c1-34(75-47(87)32-74-59(98)49(36(3)85)83-57(96)44(29-38-18-8-5-9-19-38)77-48(88)31-72-46(86)30-73-53(92)39(64)28-37-16-6-4-7-17-37)51(90)79-43(23-15-27-71-61(68)69)55(94)81-41(21-11-13-25-63)56(95)82-45(33-84)58(97)76-35(2)52(91)80-42(22-14-26-70-60(66)67)54(93)78-40(50(65)89)20-10-12-24-62/h4-9,16-19,34-36,39-45,49,84-85H,10-15,20-33,62-64H2,1-3H3,(H2,65,89)(H,72,86)(H,73,92)(H,74,98)(H,75,87)(H,76,97)(H,77,88)(H,78,93)(H,79,90)(H,80,91)(H,81,94)(H,82,95)(H,83,96)(H4,66,67,70)(H4,68,69,71)/t34-,35-,36+,39-,40-,41-,42-,43-,44-,45-,49-/m0/s1
InChI Key
RHMALYOXPBRJBG-CGUXNFSNSA-N

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