Oligopeptide-10

Oligopeptide-10 is a low molecular weight synthetic peptide composed of ten amino acids, designed for use in cosmetic formulations. Recognized for its compatibility with a range of skin care products, it supports the development of formulations targeting skin clarity and balance. Its stability in various cosmetic systems and ease of incorporation make it suitable for applications in leave-on and rinse-off products across global markets.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Oligopeptide-10(CAS 466691-40-7)

CAT No: CPO-001

CAS No:466691-40-7

Synonyms/Alias:Oligopeptide-10;UNII-Q46328TRNK;Oligopeptide-10 [INCI];Q46328TRNK;HB-64;466691-40-7;Phe-ala-lys-ala-leu-lys-ala-leu-leu-lys-ala-leu-lys-ala-leu-NH2;L-Leucinamide, L-phenylalanyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-L-lysyl-L-alanyl-;HY-P5255;DA-56423;CS-0863865;

Chemical Name:(2S)-6-amino-N-[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]propanoyl]amino]hexanamide

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C78H140N20O15
M.W/Mr.
1598.1
Sequence
One Letter Code:FAKALKALLKALKAL
Three Letter Code:H-Phe-Ala-Lys-Ala-Leu-Lys-Ala-Leu-Leu-Lys-Ala-Leu-Lys-Ala-Leu-NH2
Appearance
white or off-white powder

Mechanism of Action (MOA)

Oligopeptide-10 is a synthetic cationic peptide composed of ten amino acids. It interacts with the skin's microenvironment by modulating microbial balance and supporting the skin's innate defense mechanisms. Through selective binding to negatively charged microbial membranes, Oligopeptide-10 can influence the local skin microbiota and assist in maintaining a balanced skin barrier. Its activity is attributed to its amino acid sequence and positive charge, which contribute to its affinity for microbial cell surfaces.

Oligopeptide-10 is a versatile peptide suitable for incorporation into a variety of cosmetic formulations.

- Ideal for use in facial serums and creams
- Compatible with gel-based and emulsion systems
- Suitable for inclusion in leave-on and rinse-off products
- Can be added to targeted spot treatments
- Appropriate for daily skincare formulations
- May be incorporated into masks and overnight treatments

InChI
InChI=1S/C78H140N20O15/c1-43(2)37-59(64(84)99)94-66(101)49(12)86-72(107)56(30-20-24-34-80)91-75(110)61(39-45(5)6)96-68(103)51(14)88-74(109)58(32-22-26-36-82)93-77(112)63(41-47(9)10)98-78(113)62(40-46(7)8)97-69(104)52(15)89-73(108)57(31-21-25-35-81)92-76(111)60(38-44(3)4)95-67(102)50(13)87-71(106)55(29-19-23-33-79)90-65(100)48(11)85-70(105)54(83)42-53-27-17-16-18-28-53/h16-18,27-28,43-52,54-63H,19-26,29-42,79-83H2,1-15H3,(H2,84,99)(H,85,105)(H,86,107)(H,87,106)(H,88,109)(H,89,108)(H,90,100)(H,91,110)(H,92,111)(H,93,112)(H,94,101)(H,95,102)(H,96,103)(H,97,104)(H,98,113)/t48-,49-,50-,51-,52-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-/m0/s1
InChI Key
XWZAWHJNTHSHGD-SIDOVBMKSA-N
Canonical SMILES
CC(C)CC(C(=O)N)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(C)NC(=O)C(CC1=CC=CC=C1)N
Isomeric SMILES
C[C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC1=CC=CC=C1)N

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