Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-OH is a cysteine-derived amino acid derivative bearing a free carboxylic acid (-COOH) and a thiol-containing side chain that is modified by palmitoylation, classifying it as a lipidated, non-proteinogenic cysteine conjugate. The cysteine α-amino group remains present for further coupling chemistry, while the side chain is substituted with a palmitoyl thioether and with a (RS)-configured 2,3-di(palmitoyloxy)-propyl substituent that provides two additional ester-linked palmitate groups and a stereogenic center-bearing, highly hydrophobic tail region. In peptide and chemical biology workflows, this amphiphilic lipidated cysteine analogue is used as a building block or substrate for assembling hydrophobic peptide conjugates, membrane-mimetic constructs, and structure-activity studies where defined lipid density and stereochemical substitution patterns are required.
CAT No: CP27552
CAS No:87420-41-5
Synonyms/Alias:Pam3-Cys-OH;Palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-L-cysteine;70512-46-8;87420-41-5;Pam3Cys-OH;Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-OH;AC1L37CN;SCHEMBL483613;2,3-Bis(palmitoyloxy)-2-propyl-1-palmitoylcysteine;N-Palmitoyl-2,3-bis(palmitoyloxy)-2-propylcysteine;670820_ALDRICH;C54H103NO7S;CTK8G2255;7614AH;DA-04053;LP018825;N-|A-Palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-L-cysteine;(2R)-2-Palmitoylamino-3-[[2,3-bis(palmitoyloxy)propyl]thio]propionicacid;L-Cysteine,S-(2,3-bis((1-oxohexadecyl)oxy)propyl)-N-(1-oxohexadecyl)-;N-alpha-Palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]-L-cysteine;(2R)-3-[2,3-di(hexadecanoyloxy)propylsulfanyl]-2-(hexadecanoylamino)propanoicacid;(2R)-3-{[2,3-BIS(HEXADECANOYLOXY)PROPYL]SULFANYL}-2-HEXADECANAMIDOPROPANOICACID
4. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
5. Emu oil in combination with other active ingredients for treating skin imperfections
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More