Pegcetacoplan Acetate combines a complement-targeting peptide core with a PEGylated architecture that enhances solubility and hydrodynamic size. The conjugated polyethylene glycol segment reduces aggregation and modulates pharmacokinetic modeling in vitro. Researchers study its binding equilibria to complement proteins and structural organization in solution. Applications include complement-pathway mechanism research, ligand-protein interaction mapping, and bioconjugate optimization.
CAT No: R2537
1. TMEM16F and dynamins control expansive plasma membrane reservoirs
2. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
4. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
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