Pentapeptide-21

Pentapeptide-21 is a synthetic peptide composed of five amino acids designed for use in cosmetic formulations targeting skin care applications. Recognized for its role in supporting the skin's natural protein matrix, Pentapeptide-21 is suitable for incorporation into anti-aging, moisturizing, and skin conditioning products. Its stability and compatibility with various formulation types make it an adaptable choice for modern cosmetic product development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1755

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C29H39N5O7
M.W/Mr.
569.65
Sequence
One Letter Code: GGKGG
Three Letter Code: Gly-Gly-Lys-Gly-Gly
Appearance
white powder

Mechanism of Action (MOA)

Pentapeptide-21 is a synthetic signaling peptide composed of five amino acids. It is designed to interact with skin cells by mimicking fragments of naturally occurring extracellular matrix proteins. This peptide supports cellular communication pathways that are associated with the regulation of extracellular matrix components, such as collagen and fibronectin. Through these biochemical interactions, Pentapeptide-21 contributes to the maintenance of skin’s structural integrity and overall appearance.

Pentapeptide-21 is suitable for incorporation into a variety of cosmetic formulations targeting skin care. - Recommended for use in facial serums, creams, and lotions - Can be added to eye contour products - Compatible with both day and night skin care formulations - Suitable for inclusion in sheet masks and leave-on treatments - May be formulated into lightweight gels or emulsions - Typical use level: 0.5–2%, depending on formulation requirements

Source#
Synthetic
Long-term Storage Conditions
soluble in water

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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

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