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Protease-Activated Receptor-2, amide

Protease-Activated Receptor-2, amide (SLIGKV-NH2) is a highly potent protease-activated receptor-2 (PAR2) activating peptide.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Protease-Activated Receptor-2, amide(CAS 190383-13-2)

CAT No: R1637

CAS No:190383-13-2

Synonyms/Alias:SLIGKV-NH2;190383-13-2;H-Ser-Leu-Ile-Gly-Lys-Val-NH2;Ser-Leu-Ile-Gly-Lys-Val-amide;(2S)-6-amino-2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]hexanamide;(S)-6-Amino-2-(2-((2S,3S)-2-((S)-2-((S)-2-amino-3-hydroxypropanamido)-4-methylpentanamido)-3-methylpentanamido)acetamido)-N-((S)-1-amino-3-methyl-1-oxobutan-2-yl)hexanamide;PAR2 activating peptide;PAR2-AP;PAR-2 (1-6) Human;CHEMBL4084322;Ser-Leu-Ile-Gly-Lys-Val-NH2;BDBM85084;DTXSID70440595;CHEBI:184103;HOWDUIVVWDUEED-WAUHAFJUSA-N;HY-P0283;MFCD02259590;AKOS024457380;DA-57925;FP109317;MS-30734;CAS_190383-13-2;G13125;H-Ser-Leu-Ile-Gly-Lys-Val-NH2; H-SLIGKV-NH2;PAR-2 (1-6) amide (human) trifluoroacetate salt;Ser-Leu-Ile-Gly-Lys-Val-amide, >=95% (HPLC), solid;Protease-activated receptor 2 (PAR2) agonist(SLIGKV-NH2)?;

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M.F/Formula
C28H54N8O7
M.W/Mr.
614.8
Sequence
One Letter Code:SLIGKV
Three Letter Code:H-Ser-Leu-Ile-Gly-Lys-Val-NH2
Biological Activity
Protease-activated receptor 2 (PAR2) agonist (Ki = 9.64 μM and IC50 = 10.4 μM). Corresponds to the tethered ligand exposed by trypsin cleavage of PAR-2.
Long-term Storage Conditions
Soluble to 1 mg/ml in water
Shipping Condition
Room temperature in continental US; may vary elsewhere.
InChI
InChI=1S/C28H54N8O7/c1-7-17(6)23(36-27(42)20(12-15(2)3)34-25(40)18(30)14-37)28(43)32-13-21(38)33-19(10-8-9-11-29)26(41)35-22(16(4)5)24(31)39/h15-20,22-23,37H,7-14,29-30H2,1-6H3,(H2,31,39)(H,32,43)(H,33,38)(H,34,40)(H,35,41)(H,36,42)/t17-,18-,19-,20-,22-,23-/m0/s1
InChI Key
HOWDUIVVWDUEED-WAUHAFJUSA-N

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