PyBOP contains a phosphonium-based coupling reagent structure commonly used in peptide bond formation, functioning as an amino-acid activation reagent rather than as an amino acid itself. It bears a reactive phosphonium center that promotes formation of an activated carboxylate intermediate from an amino acid or protected amino acid derivative, supporting chemoselective coupling while minimizing side reactions associated with unactivated carboxylic acids. PyBOP is employed in solution-phase peptide synthesis and related amide coupling workflows to assemble peptide chains from amino acid building blocks, including protected amino acids and peptide intermediates used in stepwise synthesis.
CAT No: CP26289
CAS No:128625-52-5
Synonyms/Alias:PyBOP;128625-52-5;(Benzotriazol-1-yloxy)tripyrrolidinophosphoniumhexafluorophosphate;((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphoniumhexafluorophosphate(V);PyBOP(R);Benzotriazol-1-yl-oxytripyrrolidinophosphoniumhexafluorophosphate;Benzotriazole-1-yl-oxytripyrrolidinophosphoniumhexafluorophosphate;MFCD00077411;1H-Benzotriazol-1-yloxytripyrrolidinophosphoniumHexafluorophosphate;Benzotriazol-1-yloxytris(pyrrolidino)phosphoniumhexafluorophosphate;ST51007068;benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphoniumhexafluorophosphate;benzotriazol-1-yl-oxy-tripyrrolidinophosphoniumhexafluorophosphate;benzotriazol-1-yloxy-tripyrrolidino-phosphoniumhexafluorophosphate;Benzotriazol-1-yloxytripyrrolidinophosphoniumhexafluorophosphate;benzotriazol-1-yl-oxy-tris(pyrrolidino)phosphoniumhexafluorophosphate;benzotriazol-1-yl-oxy-tris-pyrrolidino-phosphoniumhexafluorophosphate;benzotriazole-1-yl-oxy-trispyrrolidinophosphoniumhexafluorophosphate;BENZOTRIAZOL-1-YL-OXYTRIPYRROLIDINO-PHOSPHONIUMHEXAFLUOROPHOSPHATE;
2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
4. Cationic cell-penetrating peptides are potent furin inhibitors
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More