Q-VD-OPH

Q-VD-OPH is a broad-spectrum caspase inhibitor that blocks caspases-3, -7, -8, -9, -10, and -12. It more effectively inhibits apoptosis and is much less cytotoxic than Z-VAD-FMK and Boc-D-FMK.

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CAT#R0812
CAS1135695-98-5
Synonyms/Aliaspan-Caspase inhibitor (fluoromethylketone); N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone
M.F/FormulaC26H25F2N3O6
M.W/Mr.513.8
ApplicationQ-VD-OPH is a selective, brain and cell permeable, highly potent and irreversible inhibitor of caspase-3 ( IC50=25nm), caspase-1 (IC50=50nM), caspase-8 (IC50=100nM) and caspase-9 (IC50=430nM).
AppearanceWhite to off-white solid powder
Purity>98% (or refer to the Certificate of Analysis)
ActivityInhibitor
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