rh-Oligopeptide-2 is a bioengineered peptide identical to a fragment of human epidermal growth factor, produced via recombinant technology. It is utilized in cosmetic formulations to support the appearance of smoother, revitalized skin by enhancing the delivery of essential signals to the epidermis. Suitable for a range of topical applications, rh-Oligopeptide-2 is compatible with various formulation types and aligns with global cosmetic regulatory requirements.
Mechanism of Action (MOA)
rh-Oligopeptide-2 is a recombinant human-derived signaling peptide that interacts with cellular receptors to support physiological communication within the epidermis. By mimicking endogenous growth factor sequences, it modulates cell-to-cell signaling pathways, encouraging balanced cellular activity. This peptide may influence processes such as keratinocyte proliferation and extracellular matrix interactions, contributing to the maintenance of healthy skin structure and function. Its activity is achieved through biochemical signaling without altering the skin’s physiological integrity.
rh-Oligopeptide-2 is suitable for incorporation into a variety of cosmetic formulations.
- Facial serums and ampoules- Lightweight emulsions and lotions- Creams for daily skincare routines- Eye area treatments- Sheet masks and leave-on gels- Pre-makeup priming products- After-sun care formulations
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.