Sar-[D-Phe8]-des-Arg9-Bradykinin is a modified bradykinin analog incorporating N-terminal sarcosine and a D-aromatic substitution that alters conformational rigidity. These modifications influence binding orientation and folding behavior. The sequence supports structure–function correlation studies. Researchers employ it in mechanistic analyses of bradykinin derivatives.
CAT No: R1099
CAS No:126959-88-4
Synonyms/Alias:126959-88-4;Sar-[D-Phe8]-des-Arg9-Bradykinin;[Sar,D-Phe8,des-Arg9]bradykinin;Bradykinin, sar-(D-phe(8))des-arg(9);1-8-Bradykinin, N2-(N-methylglycyl)-8-D-phenylalanine-;(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;Spa-BK;Sar[DPhe8][des-Arg9]BK;R-838 compound;Sar-(D-phe(8))des-arg(9)-BK;[sarcosine,D-Phe8,des-Arg9]bradykinin;[N-methylglycine,D-Phe8,des-Arg9]bradykinin;Sar[Dphe...8...][des-Arg...9...]Bradykinin;GTPL643;H-(Sar)RPPGFSP(dF)-OH;SCHEMBL20298701;BFA95988;AKOS024457495;Sar- [D-Phe8] -des-Arg9-Bradykinin;DA-57655;HY-103291;CS-0027207;Q27088695;Bradykinin, N2-(N-methylglycyl)-8-D-phenylalanine-9-de-L-arginine-;(2R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[(2-methylaminoacetyl)amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;
2. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
3. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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