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[Sar1, Ile8]-Angiotensin II

[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
[Sar1, Ile8]-Angiotensin II(CAS 37827-06-8)

CAT No: R1131

CAS No:37827-06-8

Synonyms/Alias:Sar-Arg-Val-Tyr-Ile-His-Pro-Ile;67724-27-0;Angiotensin II [Sar1 Ile8];(Sar1,Ile8)-Angiotensin II;[Sar1,Ile8]-ANGIOTENSIN II;37827-06-8;[Sar1, Ile8]-Angiotensin II;2-[[1-[2-[[2-[[2-[[2-[[5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoic acid;DTXSID80553928;PAN-4016-V;AKOS040759172;DA-69294;N-Methylglycyl-N~5~-(diaminomethylidene)ornithylvalyltyrosylisoleucylhistidylprolylisoleucine;2-{[1-(2-{2-[2-(2-{5-carbamimidamido-2-[2-(methylamino)acetamido]pentanamido}-3-methylbutanamido)-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido}-3-(1H-imidazol-4-yl)propanoyl)pyrrolidin-2-yl]formamido}-3-methylpentanoic acid;

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cGMP Peptide
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  • CMC information required for an IND
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  • Drug master files (DMF) filing
M.F/Formula
C46H73N13O10
M.W/Mr.
968.2
Sequence
One Letter Code:GRVYXHPX
Three Letter Code:H-Sar-DL-Arg-DL-Val-DL-Tyr-DL-xiIle-DL-His-DL-Pro-DL-xiIle-OH
InChI
InChI=1S/C46H73N13O10/c1-8-26(5)37(43(66)55-33(21-29-22-50-24-52-29)44(67)59-19-11-13-34(59)41(64)58-38(45(68)69)27(6)9-2)57-40(63)32(20-28-14-16-30(60)17-15-28)54-42(65)36(25(3)4)56-39(62)31(53-35(61)23-49-7)12-10-18-51-46(47)48/h14-17,22,24-27,31-34,36-38,49,60H,8-13,18-21,23H2,1-7H3,(H,50,52)(H,53,61)(H,54,65)(H,55,66)(H,56,62)(H,57,63)(H,58,64)(H,68,69)(H4,47,48,51)
InChI Key
ZVUNAQTWOGAJRE-UHFFFAOYSA-N

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