SARS-CoV T-cell Peptide Antigens Set

Name: SARS-CoV T-cell Peptide Antigens Set
Brand: Creative Peptides
SKU: S29006
Availability: MadeToOrder

The SARS-CoV T-cell peptide antigens set contains 5 peptides corresponding to SARS-CoV spike protein sequence. The sequences have been tested for HLA binding with SARS-CoV protein and includes a positive and a negative control. CV1, CV2 and CV3 sequences are also seen within the spike glycoprotein of SARS-CoV2. The peptide sequences are offered in net peptide quantities in individual vials of 0.25 mg each. The peptide epitopes can be used in ELISPOT, cytokine and CTL assays. The sequences in the set are, CV1- VLNDILSRL CV2- NLNESLIDL CV3- FIAGLIAIV CV4- KLPDDFMGCV (+ve control) CV5- AYRPPNAPIL (-ve control)

Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

CAT No: S29006

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DOTA-cyclo(RGDfK) acetate

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Terlipressin Acetate

Terlipressin acetate is a vasopressin analogue with potent vasoactive properties. Terlipressin acetate is a highly selective vasopressin V1 receptor agonist that reduces the splanchnic blood flow and portal pressure and controls acute variceal bleeding. Terlipressin acetate exerts anti-inflammatory and anti-oxidative effects. Terlipressin acetate has the potential for hepatorenal syndrome and norepinephrine-resistant septic shock research.

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Icatibant

Icatibant (Firazyr) is a synthetic peptidomimetic drug consisting of ten amino acids, and acts as an effective and specific antagonist of bradykinin B2 receptors. It has been approved in the EU for use in hereditary angioedema, and is under investigation for a number of other conditions in which bradykinin is thought to play a significant role.

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Antide

Antide acetate (Ac-AA10-NH2) is an LHRH antagonist and represses LH and FSH release from the pituitary gland. It shows a high antiovulatory activity and releases negligible histamine.

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Aviptadil Acetate

Aviptadil, also known as vasoactive intestinal polypeptide (VIP), is a 28 amino acid neuropeptide that belongs to the glucagon-growth hormone-releasing factor secretion superfamily. Aviptadil acts as a potent systemic vasodilator and bronchodilator. It inhibits the proliferation of vascular and bronchial smooth muscle cells and decreases platelet aggregation. These biological effects are mediated by specific VIP receptors.

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Atosiban

Atosiban is a nonapeptide, desamino-oxytocin analogue, and a competitive vasopressin/oxytocin receptor antagonist (VOTra). Atosiban is indicated to delay imminent pre-term birth in pregnant adult women. Atosiban is useful in improving the pregnancy outcome of in vitro fertilization-embryo transfer (IVF-ET) in patients with repeated implantation failure (RIF). The pregnancy rate improved from zero to 43.7%.

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Alarelin acetate

Alarelin acetate is a synthetic LH-RH agonist, and stimulates the release of FSH and LH from the pituitary gland. It is known for its induction of ovulation and used to treat endmometriosis.

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Angiotensin II Acetate

Angiotensin II is an octapeptide that produced from angiotensin I after the removal of two amino acids at the C-terminal by angiotensin-converting enzyme (ACE). Angiotensin II is mediated by AT1 and AT2 receptors, which are seven transmembrane glycoproteins with 30% sequence similarity.

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Glucagon

Glucagon (Porcine glucagon) is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis. Glucagon decreases the activity of HNF-4. Glucagon increases HNF4α phosphorylation.

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Somatostatin

Somatostatin is a tetradecapeptide which can suppress the growth hormone (GH) secretion and control the pituitary hormone secretion in human CNS.

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Size	0.25 mg NET peptide
References	1. Lv Y, et al. Identification of a novel conserved HLA-A* 0201-restricted epitope from the spike protein of SARS-CoV. BMC immunology. 2009 Dec 1;10(1):61.2. Ahmed SF et al. Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies. Viruses. 2020 Mar;12(3):254.