Recent advances in high-resolution sequencing have led to the discovery of unique peptides derived from mitochondrial genome. 1-2 Currently 8 peptides are identified: humanin, mitochondrial open reading frame of the 12S tRNA-c (MOTS-c), and six small humanin-like peptides (SHLP1-6). 1-2 All of these peptides are released into cytosol from mitochondria. SHLP3 shares protective effects with Humanin, such as eduction in apoptosis, generation of reactive oxygen species and improving mitochondrial metabolism. In addition, it may participate in age-related disease pathology. 1-2
CAT No: X21190
1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
4. The spatiotemporal control of signalling and trafficking of the GLP-1R
5. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
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