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Suc-Ala-Glu-Pro-Phe-AMC

Suc-Ala-Glu-Pro-Phe-AMC couples a succinylated tetrapeptide to a fluorogenic AMC reporter for monitoring serine-protease activity. The Pro-Phe motif provides selectivity toward chymotrypsin-like enzymes. Researchers measure fluorescence release to obtain kinetic parameters and specificity profiles. Applications include substrate screening, inhibitor evaluation, and assay development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Suc-Ala-Glu-Pro-Phe-AMC(CAS 142997-30-6)

CAT No: R2565

CAS No:142997-30-6

Synonyms/Alias:Suc-Ala-Glu-Pro-Phe-AMC;142997-30-6;Suc-AEPF-AMC;(4S)-4-[[(2S)-2-(3-carboxypropanoylamino)propanoyl]amino]-5-[(2S)-2-[[(2S)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-oxopentanoic acid;MFCD01318830;HY-P4359;DA-78077;FS110578;CS-0653743;

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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C36H41N5O11
M.W/Mr.
719.7
Sequence
One Letter Code:AEPF
Three Letter Code:Suc-Ala-Glu-Pro-Phe-AMC
InChI
InChI=1S/C36H41N5O11/c1-20-17-32(47)52-28-19-23(10-11-24(20)28)38-34(49)26(18-22-7-4-3-5-8-22)40-35(50)27-9-6-16-41(27)36(51)25(12-14-30(43)44)39-33(48)21(2)37-29(42)13-15-31(45)46/h3-5,7-8,10-11,17,19,21,25-27H,6,9,12-16,18H2,1-2H3,(H,37,42)(H,38,49)(H,39,48)(H,40,50)(H,43,44)(H,45,46)/t21-,25-,26-,27-/m0/s1
InChI Key
HOKKGJXGOTWVKM-ZYEMSUIVSA-N

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