Tfa-Phe-OMe contains a phenylalanine-derived amino acid ester framework in which the carboxyl group is converted to a methyl ester (Phe-OMe) and the amino functionality is acylated by trifluoroacetic acid (Tfa), yielding a Tfa-protected amino ester. The molecule features a benzyl side chain bearing a hydrophobic aromatic group, along with the ester carbonyl and the trifluoroacetamide linkage, which together modulate polarity and chemoselectivity during peptide-related transformations. As an amino acid ester bearing an N-acyl protecting group, it is used as a defined building block or intermediate for preparing further peptide derivatives and for analytical or synthetic studies that require controlled reactivity of the amino and carboxyl functionalities.
1. Implications of ligand-receptor binding kinetics on GLP-1R signalling
2. Myotropic activity of allatostatins in tenebrionid beetles
4. High fat diet and GLP-1 drugs induce pancreatic injury in mice
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