Threo-D-β-Hydroxynorleucine is a non-proteinogenic, threo-configured D-amino acid featuring a straight-chain norleucine backbone bearing a β-hydroxyl substituent, which introduces an additional hydrogen-bonding and polarity element relative to the parent amino acid. The molecule contains an amino group and a carboxyl group on the α-carbon framework, with the β-hydroxyl side chain capable of participating in hydrogen bonding and forming reversible interactions with other functional groups during peptide assembly or analytical characterization. In research workflows, this β-hydroxy amino acid is used as a defined building block for incorporating hydroxylated side chains into peptides and peptide analogues, supporting structure-activity studies, chemical biology labeling strategies, and comparative synthesis of hydroxy-substituted amino acid derivatives.
CAT No: CP07204
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