Thrombospondin-derived Peptide; Cyclic CSVTCG

This peptide is derived from thrombospondin and represents a binding motif responsible for thrombospondin-CD36 interaction. It is cyclized through a disulfide bond. Thrombospondin is a matrix-bound glycoprotein involved in cancer metastasis, tumor adhesion, and angiogenesis. This peptide has been shown to competitively inhibit platelet aggregation and tumor metastasis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21211

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
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  • Drug master files (DMF) filing
M.W/Mr.
566.7
Sequence
One Letter Code: CSVTCG (S-S Bonded)
Three Letter Code: H-Cys-Ser-Val-Thr-Cys-Gly-OH(S-S Bonded)
References
1. Wakiyama, T. et al. Histol Histopathol 16, 345 (2001);
2. Tsuzynski, G. et al. J Cell Biol 120, 513 (1993);
3. Asch, A. et al. Biochem Biophys Res Commun 182, 1208 (1992).

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