Thymocartin is a regulatory peptide composed of polar, aromatic, and charged residues that modulate flexibility and secondary-structure formation. Researchers examine its conformational adaptability, protein-interface behavior, and side-chain cooperation. The motif supports biophysical mapping and mechanistic evaluation. Its sequence allows high-resolution analytical characterization.
CAT No: R2234
CAS No:85466-18-8
Synonyms/Alias:Thymocartin;85466-18-8;Thymocartine;Thymocartin [INN];Thymocartina;Thymocartinum;Arg-Lys-Asp-Val;Thymocartine [INN-French];Thymocartinum [INN-Latin];Thymocartina [INN-Spanish];Rgh 0206;timocartina;H-arg-lys-asp-val-oh;UNII-M0H0SK3AD5;RGH-0206;M0H0SK3AD5;DTXSID20234688;N-(N-(N(sup 2)-L-Arginyl-L-lysyl)-L-alpha-aspartyl)-L-valine;(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoic acid;L-Valine, N-(N-(N2-L-arginyl-L-lysyl)-L-alpha-aspartyl)-;L-Valine, N-(N-(N(sup 2)-L-arginyl-L-lysyl)-L-alpha-aspartyl)-;THYMOPOIETIN II (32-35);Thymocartine (INN-French);Thymocartinum (INN-Latin);Thymocartina (INN-Spanish);(6S,9S,12S,15S)-1,6-diamino-9-(4-aminobutyl)-12-(carboxymethyl)-1-imino-15-isopropyl-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid;N-(N-(N2-L-ARGINYL-L-LYSYL)-L-.ALPHA.-ASPARTYL)-L-VALINE;TP4 peptide;TP-4 tetrapeptide;thymopoietin (32-35);arginyl-lysyl-aspartyl-valine;RGH 0206; TP 4;SCHEMBL443972;CHEMBL2104516;DTXCID50157179;AKOS040754200;HY-105025;CS-0024724;NS00120768;Q27283305;N-(N-(N2-L-ARGINYL-L-LYSYL)-L-ALPHA-ASPARTYL)-L-VALINE;
Thymocartin is a synthetic peptide fragment derived from thymopoietin, recognized for its role as an immunomodulatory agent in biochemical and cellular research. As a well-defined peptide, it comprises a specific amino acid sequence that serves as a useful model for investigating peptide structure-activity relationships and immune system regulation. Its molecular characteristics enable precise manipulation in vitro, making it a valuable tool for researchers focused on the molecular mechanisms of immune modulation, peptide signaling, and cell differentiation. The compound's relevance extends to studies on thymic peptides and their influence on lymphocyte biology, supporting a range of experimental applications in immunology and peptide science.
Immunological research: Thymocartin is widely employed in studies exploring the regulation and differentiation of T-lymphocytes. Its defined sequence allows researchers to dissect the pathways by which thymic peptides influence immune cell maturation and function. By serving as a model peptide, it facilitates the elucidation of signaling cascades involved in immune modulation, enabling a better understanding of the molecular basis of immune system development and homeostasis.
Peptide structure-activity relationship studies: The unique sequence of this peptide makes it an ideal candidate for investigations into the relationship between peptide structure and biological activity. Researchers utilize it to analyze how specific amino acid arrangements affect receptor binding, stability, and downstream biological responses. Such studies are critical for advancing peptide-based drug design and for generating insights into the biophysical properties that govern peptide-receptor interactions.
Cell culture applications: In vitro experiments often incorporate thymic peptides to modulate cellular environments and study immune cell behavior under controlled conditions. Thymocartin can be added to lymphocyte cultures to assess its effects on proliferation, differentiation, and cytokine production. These applications are essential for developing robust models of immune function and for screening potential immunomodulatory compounds in a reproducible laboratory setting.
Peptide synthesis and analytical validation: Thymocartin serves as a reference standard and test substrate in peptide synthesis and analytical method development. Its well-characterized sequence and predictable behavior provide a benchmark for evaluating synthetic protocols, chromatographic separation, and mass spectrometric analysis. This utility supports quality control in peptide manufacturing and helps refine analytical techniques for both research and industrial applications.
Mechanistic studies in peptide signaling: The compound's capacity to mimic natural thymic factors makes it valuable for dissecting intracellular signaling mechanisms. Researchers use it to probe the activation of second messenger systems, phosphorylation events, and gene expression changes triggered by peptide-receptor engagement. These mechanistic insights contribute to a deeper understanding of peptide-mediated communication within the immune system and beyond, supporting the development of novel research tools and experimental strategies.
1. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry
2. The spatiotemporal control of signalling and trafficking of the GLP-1R
3. Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More