CAT# | T2814 |
Chemical Structure | |
CAS | 77591-33-4 |
Synonyms/Alias | FX (human, bovine, horse, rat) |
M.F/Formula | C212H350N56O78S |
M.W/Mr. | 4963.49 |
Sequence | One Letter Code: SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES |
Biological Activity | Naturally occuring, potent regulator of actin polymerization present in human platelets at a concentration of 200 - 500 μM. Sequesters G-actin monomers in a 1:1 ratio (Kd = 0.7 - 1.0 μM) and allows rapid filament polymerization in the presence of profilin. Implicated in wound healing, induction of MMPs, chemotaxis, angiogenesis, inflammatory processes and tumor progression. |
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