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Tos-Gly-OH

Tos-Gly-OH is a glycine derivative bearing a tosyl (p-toluenesulfonyl, Tos) protecting group on the amino functionality and a free carboxylic acid (OH) at the C-terminus, corresponding to a protected amino acid intermediate. The molecule contains an N-sulfonyl sulfonamide linkage that masks the α-amino group to reduce undesired side reactions during coupling chemistry, while retaining the carboxyl group for controlled activation and subsequent bond formation, with stereochemistry not specified in the name. Tos-Gly-OH is used in peptide and amide synthesis workflows as a building block where chemoselective handling of the carboxylic acid is required and the sulfonyl protection supports stepwise assembly of glycine-containing structures.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26174

CAS No:1080-44-0

Synonyms/Alias:N-p-Tosylglycine;1080-44-0;2-(4-Methylphenylsulfonamido)aceticacid;N-(p-Toluenesulfonyl)glycine;N-[(4-methylphenyl)sulfonyl]glycine;N-Tosylglycine;Tos-Gly-OH;CHEMBL287486;N-(toluene-4-sulfonyl)-glycine;VDKFCCZUCXYILI-UHFFFAOYSA-N;(Toluene-4-sulfonylamino)-aceticacid;2-[(4-methylphenyl)sulfonylamino]aceticacid;F0020-0600;Glycine,N-((4-methylphenyl)sulfonyl)-;Glycine,N-[(4-methylphenyl)sulfonyl]-;tosyl-glycine;N-4-Tosylglycine;NSC25821;PubChem23322;AC1L2EJY;AC1Q2LOM;AC1Q2LON;ACMC-2098yp;AC1Q6U5J;Oprea1_169137

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cGMP Peptide
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M.F/Formula
C9H11NO4S
M.W/Mr.
229.26
Size
25 g;100 g;
InChI
1S/C9H11NO4S/c1-7-2-4-8(5-3-7)15(13,14)10-6-9(11)12/h2-5,10H,6H2,1H3,(H,11,12)
InChI Key
VDKFCCZUCXYILI-UHFFFAOYSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)O

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