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Tos-Gly-OSu

Tos-Gly-OSu contains a glycine residue linked to a tosyl (p-toluenesulfonyl) group and an activated N-hydroxysuccinimide ester (OSu), placing the molecule in the class of amino acid derivatives designed for acyl transfer. The structure features a carbonyl activated as an NHS ester for nucleophilic acyl substitution, while the glycine portion provides an amino acid backbone motif and the tosyl substituent contributes a sulfonyl aromatic leaving-group/aryl sulfonyl functionality rather than a free carboxyl group. Tos-Gly-OSu is used as an activated glycine-based acylating reagent in peptide coupling workflows and in chemical labeling or bioconjugation contexts where an NHS-ester handle enables attachment of the glycine carbonyl to nucleophilic amines under controlled conditions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25988

CAS No:68385-26-2

Synonyms/Alias:Tos-Gly-OSu;68385-26-2;2,5-Dioxopyrrolidin-1-yl2-(4-methylphenylsulfonamido)acetate;2,5-dioxopyrrolidin-1-yl2-(4-methylbenzenesulfonamido)acetate;AmbotzTAA1510;C13H14N2O6S;CTK8G3515;MolPort-008-269-289;ZINC2526303;0553AC;KM1201;AKOS016003132;AK-81307;AM030887;HE021354;KB-225975;FT-0698828;3B3-062500;N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-4-methylbenzenesulfonamide

Chemical Name:N-alpha-p-Toluolsulfonyl-glycin N-hydroxysuccinimidyl ester

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M.F/Formula
C13H14N2O6S
M.W/Mr.
326,32 g/mole
Size
5 g;25 g;
InChI
1S/C13H14N2O6S/c1-9-2-4-10(5-3-9)22(19,20)14-8-13(18)21-15-11(16)6-7-12(15)17/h2-5,14H,6-8H2,1H3
InChI Key
NTDCTADMSAKZGL-UHFFFAOYSA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)ON2C(=O)CCC2=O

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