Tos-Gly-OSu

Name: Tos-Gly-OSu
Brand: Creative Peptides
Rating: 5 (1 reviews)

Tos-Gly-OSu contains a glycine residue linked to a tosyl (p-toluenesulfonyl) group and an activated N-hydroxysuccinimide ester (OSu), placing the molecule in the class of amino acid derivatives designed for acyl transfer. The structure features a carbonyl activated as an NHS ester for nucleophilic acyl substitution, while the glycine portion provides an amino acid backbone motif and the tosyl substituent contributes a sulfonyl aromatic leaving-group/aryl sulfonyl functionality rather than a free carboxyl group. Tos-Gly-OSu is used as an activated glycine-based acylating reagent in peptide coupling workflows and in chemical labeling or bioconjugation contexts where an NHS-ester handle enables attachment of the glycine carbonyl to nucleophilic amines under controlled conditions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25988

CAS No:68385-26-2

Synonyms/Alias:Tos-Gly-OSu;68385-26-2;2,5-Dioxopyrrolidin-1-yl2-(4-methylphenylsulfonamido)acetate;2,5-dioxopyrrolidin-1-yl2-(4-methylbenzenesulfonamido)acetate;AmbotzTAA1510;C13H14N2O6S;CTK8G3515;MolPort-008-269-289;ZINC2526303;0553AC;KM1201;AKOS016003132;AK-81307;AM030887;HE021354;KB-225975;FT-0698828;3B3-062500;N-[2-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-4-methylbenzenesulfonamide

Chemical Name:N-alpha-p-Toluolsulfonyl-glycin N-hydroxysuccinimidyl ester

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C13H14N2O6S

M.W/Mr.

326,32 g/mole

Size

5 g;25 g;

InChI

1S/C13H14N2O6S/c1-9-2-4-10(5-3-9)22(19,20)14-8-13(18)21-15-11(16)6-7-12(15)17/h2-5,14H,6-8H2,1H3

InChI Key

NTDCTADMSAKZGL-UHFFFAOYSA-N

Canonical SMILES

CC1=CC=C(C=C1)S(=O)(=O)NCC(=O)ON2C(=O)CCC2=O

1. Myotropic activity of allatostatins in tenebrionid beetles

2. Immune responses to peptides containing homocitrulline or citrulline in the DR4-transgenic mouse model of rheumatoid arthritis

3. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum

4. High fat diet and GLP-1 drugs induce pancreatic injury in mice

5. Extended exenatide administration enhances lipid metabolism and exacerbates pancreatic injury in mice on a high fat, high carbohydrate diet

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