Ubrogepant, also known as MK-1602, is a potent and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist.
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Synonyms/Alias | MK-1602; MK 1602; MK1602 |
M.F/Formula | C29H26F3N5O3 |
M.W/Mr. | 549.5542 |
Labeling Target | Histone deacetylase |
Application | Ubrogepant is investigated for acute treatment of migraines. |
Appearance | Solid powder |
Purity | >98% (or refer to the Certificate of Analysis) |
Activity | Antagonist |
Biological Activity | Ubrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. |
Target | CGRP Receptor |
Source# | Synthetic |
Long-term Storage Conditions | Soluble in DMSO, not in water |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Short-term Storage Conditions | Dry, dark and at 0 - 4 °C |
Solubility | -20 °C |
InChI | InChI=1S/C29H26F3N5O3/c1-16-20(17-6-3-2-4-7-17)11-22(26(39)37(16)15-29(30,31)32)35-25(38)19-10-18-12-28(13-23(18)34-14-19)21-8-5-9-33-24(21)36-27(28)40/h2-10,14,16,20,22H,11-13,15H2,1H3,(H,35,38)(H,33,36,40)/t16-,20-,22+,28+/m1/s1 |
InChI Key | DDOOFTLHJSMHLN-ZQHRPCGSSA-N |
Isomeric SMILES | C[C@@H]1[C@@H](C[C@@H](C(=O)N1CC(F)(F)F)NC(=O)C2=CC3=C(C[C@@]4(C3)C5=C(NC4=O)N=CC=C5)N=C2)C6=CC=CC=C6 |
BoilingPoint | 942.8±65.0 °C at 760 mmHg |
ShelfLife | >2 years if stored properly |
Melting Point | N/A |
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