Ubrogepant

Ubrogepant, also known as MK-1602, is a potent and selective oral calcitonin gene-related peptide (CGRP) receptor antagonist.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-185

CAS No:1374248-77-7

Synonyms/Alias:MK-1602; MK 1602; MK1602

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C29H26F3N5O3
M.W/Mr.
549.5542
Labeling Target
Histone deacetylase
Application
Ubrogepant is investigated for acute treatment of migraines.
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Activity
Antagonist
Biological Activity
Ubrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine.
Target
CGRP Receptor
Source#
Synthetic
Long-term Storage Conditions
Soluble in DMSO, not in water
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Short-term Storage Conditions
Dry, dark and at 0 - 4 °C
Solubility
-20 °C
InChI
InChI=1S/C29H26F3N5O3/c1-16-20(17-6-3-2-4-7-17)11-22(26(39)37(16)15-29(30,31)32)35-25(38)19-10-18-12-28(13-23(18)34-14-19)21-8-5-9-33-24(21)36-27(28)40/h2-10,14,16,20,22H,11-13,15H2,1H3,(H,35,38)(H,33,36,40)/t16-,20-,22+,28+/m1/s1
InChI Key
DDOOFTLHJSMHLN-ZQHRPCGSSA-N
Isomeric SMILES
C[C@@H]1[C@@H](C[C@@H](C(=O)N1CC(F)(F)F)NC(=O)C2=CC3=C(C[C@@]4(C3)C5=C(NC4=O)N=CC=C5)N=C2)C6=CC=CC=C6
BoilingPoint
942.8±65.0 °C at 760 mmHg
ShelfLife
>2 years if stored properly
Melting Point
N/A

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