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XG 102

XG-102, a TAT-coupled dextrogyre peptide inhibiting the c-Jun N-terminal kinase, was shown efficient in the treatment of experimental uveitis. Research show that XG-102 peptide has potential for treating intraocular inflammation.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-141

CAS No:1198367-70-2

Synonyms/Alias:AM 111;XG 102 peptide;D-JNKI-1

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cGMP Peptide
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  • CMC information required for an IND
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  • Drug master files (DMF) filing
M.F/Formula
C164H285N65O41
M.W/Mr.
3823.49
Sequence
H-D-Asp-D-Gln-D-Ser-D-Arg-D-Pro-D-Val-D-Gln-D-Pro-D-Phe-D-Leu-D-Asn-D-Leu-D-Thr-D-Thr-D-Pro-D-Arg-D-Lys-D-Pro-D-Arg-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-Gly-OH
Labeling Target
c-Jun N-terminal kinase (JNK)
Activity
Inhibitor
Biological Activity
XG-102, a TAT-coupled dextrogyre peptide inhibiting the c-Jun N-terminal kinase, was shown efficient in the treatment of experimental uveitis.
Areas of Interest
Inflammation
Target
JNK

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