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Z-D-Gln(Trt)-OH

Z-D-Gln(Trt)-OH is a protected amino acid derivative featuring a D-configured glutamine backbone bearing an N-benzyloxycarbonyl (Z) protecting group and a trityl (Trt) protecting group on the side-chain amide functionality. The molecule contains a free carboxylic acid group and a protected amino group, with the Trt-protected side-chain amide reducing hydrogen-bonding and chemoselectively masking the glutamine side chain during peptide assembly. Z-D-Gln(Trt)-OH is used as a building block in stepwise peptide synthesis and related peptide chemistry workflows where orthogonal protection and controlled deprotection of the side-chain amide are required for incorporation of a glutamine residue.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26663

CAS No:200625-96-3

Synonyms/Alias:200625-96-3;ZINC15721692;D-Glutamine,N2-[(phenylmethoxy)carbonyl]-N-(triphenylmethyl)-

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M.F/Formula
C32H30N2O5
M.W/Mr.
522.61
Size
1 g;5 g;25 g;
InChI
1S/C32H30N2O5/c35-29(22-21-28(30(36)37)33-31(38)39-23-24-13-5-1-6-14-24)34-32(25-15-7-2-8-16-25,26-17-9-3-10-18-26)27-19-11-4-12-20-27/h1-20,28H,21-23H2,(H,33,38)(H,34,35)(H,36,37)/t28-/m1/s1
InChI Key
MYOAIKMOWHPBQS-MUUNZHRXSA-N
Canonical SMILES
C1=CC=C(C=C1)COC(=O)NC(CCC(=O)NC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C(=O)O

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