Z-D-Nle-ONp is a protected amino acid derivative in which the amino group of D-norleucine (Nle) is masked by a benzyloxycarbonyl (Z, Cbz) protecting group and the carboxyl group is converted to an ONp ester (para-nitrophenyl ester). The molecule therefore bears a carbamate-linked Z group on nitrogen and an activated para-nitrophenyl ester at the carboxyl terminus, with stereochemistry specified as D at the α-carbon. Z-D-Nle-ONp is used as an amino-acid building block and activated ester intermediate for peptide coupling and related synthesis workflows, where the ONp ester provides a leaving group suitable for forming amide bonds under appropriate conditions.
CAT No: CP26984
CAS No:31062-20-1
Synonyms/Alias:Z-D-Nle-ONp;31062-20-1;Z-D-norleucine4-nitrophenylester;96950_ALDRICH;96950_FLUKA;ZINC2522556;7892AH;Z-D-2-aminohexanoicacid-p-nitrophenylester;K-7386
1. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
2. Implications of ligand-receptor binding kinetics on GLP-1R signalling
5. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More