Z-D-Phe-ONp is a protected D-phenylalanine derivative in which the amino group is masked by a benzyloxycarbonyl (Z, Cbz) protecting group and the carboxyl group is converted to an ONp ester (p-nitrophenyl ester). The molecule contains a stereochemically defined D-α-amino acid backbone bearing a benzyl side chain, with the Z carbamate and the p-nitrophenyl ester providing chemoselective handling of the amine and carboxyl functionalities. Z-D-Phe-ONp is used as an amino acid ester building block for peptide coupling and for preparing more complex phenylalanine-containing derivatives, and the p-nitrophenyl ester form provides a leaving group suitable for acyl transfer under standard peptide synthesis conditions.
CAT No: CP25674
CAS No:2578-85-0
Synonyms/Alias:Z-D-PHE-ONP;2578-85-0;ST51037725;SCHEMBL7327394;CHEMBL3278860;MolPort-008-269-450;TVENQUPLPBPLGU-OAQYLSRUSA-N;ZINC1708436;AKOS024386424;N-Cbz-D-Phenylalaninep-nitrophenylester;N-CBZ-D-Phenylalanine4-nitrophenylester;V4723;K-6728;Nalpha-benzyloxycarbonyl-D-phenylalaninep-nitrophenylester;4-nitrophenyl(2R)-3-phenyl-2-[(phenylmethoxy)carbonylamino]propanoate
Chemical Name:N-alpha-Benzyloxycarbonyl-D-phenylalanine p-nitrophenyl ester
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