Z-D-Ser(tBu)-OMe is a protected, derivatized amino acid where the side-chain corresponds to serine and the amino group is masked as a benzyloxycarbonyl (Z/Cbz-type) carbamate, while the carboxyl functionality is present as a methyl ester (-OMe). The molecule bears a tert-butyl substituent on the serine side chain (tBu-protected hydroxymethyl group), and the stereochemical descriptor "D" indicates the D-configuration at the alpha carbon, with both the carbamate and ester groups reducing free amine and free carboxyl reactivity. Z-D-Ser(tBu)-OMe is used as a stepwise peptide-synthesis building block or intermediate in protected amino acid strategies, where the orthogonal protection pattern supports controlled coupling and later deprotection to reveal the serine side-chain hydroxyl for subsequent functionalization or incorporation into peptide derivatives.
CAT No: CP27592
CAS No:93204-37-6
Synonyms/Alias:Z-D-SER(TBU)-OME;93204-37-6;D-Serine,O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-,methylester;Z-D-SER-OME;SCHEMBL344382;CTK8G3893;UMAXPCYVVRYQNO-CYBMUJFWSA-N;ZINC2560791;7895AH;KM3172;Z-O-tert-butyl-D-serinemethylester;AKOS025289415;AK170162;FT-0699231;(R)-methyl2-(benzyloxycarbonylamino)-3-t-butoxypropanoate
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