Z-Glu(OMe)-OSu is a protected glutamic acid derivative in which the α-amino group is masked as a Z (benzyloxycarbonyl/Cbz-type) carbamate and the side-chain carboxyl is present as a methyl ester (Glu(OMe)). The molecule contains an activated N-hydroxysuccinimide (OSu) ester functionality at the carboxyl position, providing a leaving group for amide bond formation, while the Z-protecting group controls chemoselectivity by reducing undesired reactions at the amino site. Z-Glu(OMe)-OSu is used as an amino-acid building block for preparing peptide and amide derivatives, including coupling steps in solution-phase or solid-supported syntheses where the OSu ester form supports controlled acyl transfer to nucleophiles such as amines.
CAT No: CP27079
CAS No:39538-31-3
Synonyms/Alias:Z-GLU(OME)-OSU;39538-31-3;C18H20N2O8;7904AH;ZINC100236155;K-8497;(S)-5-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-5-oxo-4-[[(benzyloxy)carbonyl]amino]valericacidmethylester
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