Z-glycine

Z-glycine contains glycine bearing a Z (benzyloxycarbonyl, Cbz) protecting group on the amino functionality, classifying it as a protected amino acid derivative rather than a free amino acid. The molecule features a carboxylic acid group and a carbamate-protected primary amine, with the benzyloxycarbonyl moiety providing chemoselectivity by reducing undesired side reactions during peptide-coupling steps. Z-glycine is employed as a building block in peptide synthesis and related amino acid coupling workflows, where controlled handling of the protected amino group supports stepwise assembly of peptide or peptidomimetic structures.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00911

CAS No:1138-80-3

Synonyms/Alias:N-Carbobenzyloxyglycine;N-CBZ-glycine;1138-80-3;Carbobenzyloxyglycine;Carbobenzoxyglycine;Cbz-Gly-OH;(Cbz)gly;N-Carbobenzoxyglycine;N-Benzyloxycarbonylglycine;Z-Gly-OH;Benzyloxycarbonylglycine;Z-Gly;Z-Glycine;Cbz-Glycine;N-CarboxyglycineN-benzylester;Carbobenzoxylglycine;Glycine,N-[(phenylmethoxy)carbonyl]-;N-(benzyloxycarbonyl)glycine;N-Carbobenzoxy-Glycine;2-{[(benzyloxy)carbonyl]amino}aceticacid;Benzyloxycarbonylamino-AceticAcid;2-(BENZYLOXYCARBONYLAMINO)ACETICACID;NSC2526;2-(((benzyloxy)carbonyl)amino)aceticacid;N-[(benzyloxy)carbonyl]glycine

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cGMP Peptide
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  • Drug master files (DMF) filing
M.F/Formula
C10H11NO4
M.W/Mr.
209.2
Abbr
Z-Gly-OH
InChI
1S/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
InChI Key
CJUMAFVKTCBCJK-UHFFFAOYSA-N
Canonical SMILES
C1=CC=C(C=C1)COC(=O)NCC(=O)O

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