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Z-L-Arg-AMC*HCl

Z-L-Arg-AMC*HCl contains an L-arginine-derived amino acid amide linked to 7-amino-4-methylcoumarin (AMC), with the α-amino group protected as a Z (benzyloxycarbonyl) carbamate and present as a hydrochloride salt. The molecule bears the guanidinium side chain characteristic of arginine, an amide linkage to the fluorogenic coumarin reporter, and a free carboxylate equivalent consistent with the amino acid amide framework, while the "*" indicates a specified structural variant of the AMC reporter as supplied by the product identity. Z-L-Arg-AMC*HCl is used as a substrate analog in biochemical assay development and enzyme-substrate studies where the coumarin moiety provides a fluorescent readout upon cleavage, and it is also employed in analytical and chemical biology workflows that require defined arginine-AMC reporter conjugates.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26000

CAS No:70375-22-3

Synonyms/Alias:Z-Arg-MCA;70375-22-3;Z-L-Arg7-amido-4-methylcoumarinhydrochloride;Z-L-Arginine-4-methyl-7-coumarinylamidehydrochloride;Carbobenzoxy-L-arginine-7-amino-4-methylcoumarinhydrochloride;N-alpha-CBZ-L-Arginine7-amido-4-methylcoumarinhydrochloride;Z-Arg-AmcHCl;Z-ARG-AMCHCL;C8022_SIGMA;SCHEMBL380911;EINECS274-586-3;FT-0629951;Nalpha-Cbz-L-arginine7-amido-4-methylcoumarinhydrochloride;Benzyl(S)-(4-(amidinoamino)-1-(((4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino)carbonyl)butyl)carbamatemonohydrochloride;Carbamicacid,[(1S)-4-[(aminoiminomethyl)amino]-1-[[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl]butyl]-,phenylmethylester,monohydrochloride(9CI)

Chemical Name:N-alpha-Benzyloxycarbonyl-L-arginine 7-amido-4-methylcoumarin hydrochloride, 99%

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M.F/Formula
C24H28ClN5O5
M.W/Mr.
465,50*36,45 g/mole
Size
250 mg;
InChI
1S/C24H27N5O5.ClH/c1-15-12-21(30)34-20-13-17(9-10-18(15)20)28-22(31)19(8-5-11-27-23(25)26)29-24(32)33-14-16-6-3-2-4-7-16;/h2-4,6-7,9-10,12-13,19H,5,8,11,14H2,1H3,(H,28,31)(H,29,32)(H4,25,26,27);1H/t19-;/m0./s1
InChI Key
JYWCRDUTYUBXOL-FYZYNONXSA-N
Canonical SMILES
CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C(CCCN=C(N)N)NC(=O)OCC3=CC=CC=C3.Cl

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