Z-L-glutamic acid γ-tert.butyl α-benzyl ester

Z-L-glutamic acid γ-tert.butyl α-benzyl ester is a protected, esterified derivative of L-glutamic acid in which the α-carboxyl group is converted to a benzyl ester and the γ-carboxyl group is converted to a tert-butyl ester, while the amino functionality is masked as a Z (benzyloxycarbonyl) carbamate. The molecule therefore contains a carbamate-protected α-amino group and two ester-protected carboxyl groups with benzyl and tert-butyl groups that can be removed under appropriate deprotection conditions, leaving the corresponding free amines and carboxylic acids for further transformations. This structure is commonly employed as a stepwise building block in peptide and amino-acid derivative synthesis, including workflows that require orthogonal protection of glutamate side-chain carboxyl functionality for controlled coupling and selective deprotection.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00749

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.W/Mr.
427.5
Abbr
Z-Glu(OtBu)-OBzl

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