Z-L-glutamic acid γ-tert.butyl α-benzyl ester is a protected, esterified derivative of L-glutamic acid in which the α-carboxyl group is converted to a benzyl ester and the γ-carboxyl group is converted to a tert-butyl ester, while the amino functionality is masked as a Z (benzyloxycarbonyl) carbamate. The molecule therefore contains a carbamate-protected α-amino group and two ester-protected carboxyl groups with benzyl and tert-butyl groups that can be removed under appropriate deprotection conditions, leaving the corresponding free amines and carboxylic acids for further transformations. This structure is commonly employed as a stepwise building block in peptide and amino-acid derivative synthesis, including workflows that require orthogonal protection of glutamate side-chain carboxyl functionality for controlled coupling and selective deprotection.
CAT No: CP00749
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