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Z-L-Phe-ONp

Z-L-Phe-ONp is a protected amino acid derivative consisting of L-phenylalanine bearing a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality and an ONp ester at the carboxyl terminus (ONp = p-nitrophenyl ester). The molecule contains the aromatic side chain of phenylalanine and features a carbamate-protected α-amino group alongside an activated carboxylate ester, with the stereochemistry indicated as L for the α-carbon. Z-L-Phe-ONp is used as an amino acid building block in peptide synthesis and as an activated ester intermediate for acylation steps in solution-phase coupling and related derivatization workflows.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25673

CAS No:2578-84-9

Synonyms/Alias:Z-Phe-ONp;2578-84-9;Z-L-phenylalanine4-nitrophenylester;2578-86-1;4-nitrophenyl(2S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanoate;AmbotzZAA1236;Z-Phe-4-npe;AC1L45IL;Benzyloxycarbonylphenylalanine4-nitrophenylester;Z-L-Phe-(p-Nitrophenyl)OH;SCHEMBL1715348;CHEMBL3278846;97022_FLUKA;CTK4F6444;MolPort-003-939-983;TVENQUPLPBPLGU-NRFANRHFSA-N;ZINC2575525;7955AH;AM021214;N-benzyloxycarbonyl-L-phenylalaninep-nitrophenylester;N-benzyloxycarbonyl-L-phenylalanine-p-nitrophenylester;N-benzyloxycarbonyl-L-phenylalanine4-nitrophenylester;Phenylalanine,N-[(phenylmethoxy)carbonyl]-,4-nitrophenylester;DL-Phenylalanine,N-((phenylmethoxy)carbonyl)-,4-nitrophenylester;(4-nitrophenyl)(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate

Chemical Name:N-alpha-Benzyloxycarbonyl-L-phenylalanine p-nitrophenyl ester

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M.F/Formula
C23H20N2O6
M.W/Mr.
420,42 g/mole
Size
5 g;25 g;
InChI
1S/C23H20N2O6/c26-22(31-20-13-11-19(12-14-20)25(28)29)21(15-17-7-3-1-4-8-17)24-23(27)30-16-18-9-5-2-6-10-18/h1-14,21H,15-16H2,(H,24,27)/t21-/m0/s1
InChI Key
TVENQUPLPBPLGU-NRFANRHFSA-N
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)OCC3=CC=CC=C3

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