Z-N-α-methyl-L-Phenylalanine is a protected, Nα-methylated amino acid derivative in which the phenylalanine side chain (benzyl group) is retained while the α-position bears a methyl substituent, altering backbone sterics and conformational behavior. The molecule contains an N-protecting Z (benzyloxycarbonyl/Cbz-type) group on the amino functionality and a free carboxyl group, with the stereochemistry indicated as L at the α-carbon. It is used as a building block for peptide synthesis and related structure-activity studies where an α-methylated, sterically constrained phenylalanine analogue is incorporated to probe effects on peptide conformation, stability, and side-chain presentation.
CAT No: CP01644
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