Z-O-tert.butyl-L-threonine tert.butyl ester is a protected threonine derivative in which the threonine amino acid backbone is converted to a tert-butyl ester at the carboxyl group and the side-chain hydroxyl is masked as an O-tert-butyl ether, with the L stereochemical form indicated in the name. The molecule contains a free amino group as part of the Z-protected functionality (carbobenzyloxy/benzyloxycarbonyl protection) and retains the threonine β-hydroxyl functionality only in masked form, while the tert-butyl groups provide steric and acid/base stability characteristic of tert-butyl ether and tert-butyl ester protecting patterns. As a stepwise peptide-synthesis intermediate and protected amino acid building block, it supports controlled chemoselectivity by keeping the amino and carboxyl functions in protected forms and by suppressing side-chain hydroxyl reactivity during coupling and subsequent assembly of peptide derivatives.
CAT No: CP01929
CAS No:14437-51-5
Synonyms/Alias:14437-51-5;ZINC2556684;AM82262;Z-O-tert.butyl-L-threoninetert.butylester;L-Threonine,O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-,1,1-dimethylethylester
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