Z-p-fluoro-Phe-chloromethylketone is a protected phenylalanine-derived chloromethyl ketone in which the phenylalanine side chain is substituted with a para-fluorine atom and the amino group is masked by a Z (benzyloxycarbonyl) protecting group. The molecule contains a chloromethyl ketone electrophile (-CO-CH2Cl) attached to the amino acid framework, along with the Z-carbamate functionality that limits free amine reactivity while retaining the carboxyl-derived carbonyl within the ketone motif. As an amino-acid-based electrophilic probe and peptide-synthesis intermediate, it can be employed for chemical biology and structure-activity studies that require controlled installation of a fluorinated phenylalanine residue and a chloromethyl ketone functional handle for covalent labeling or inhibitor design workflows.
CAT No: CP27084
CAS No:400771-48-4
Synonyms/Alias:Z-L-p-Fluoro-Phe-chloromethylketone;400771-48-4;PubChem11549;SCHEMBL6489247;SSXSAFSLNOWRIX-INIZCTEOSA-N;ZINC2561189;7935AH;FT-0603931;K-8572;(3S)-3-Benzyloxycarbonylamino-1-chloro-4-(p-fluorophenyl)-2-butanone;(3S)-3-Benzyloxycarbonylamino-1-chloro4-(p-fluorophenyl)-2-butanone
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