Z-Sar-OSu is a protected amino acid derivative in which Sar (sarcosine, N-methylglycine) is converted to an activated N-hydroxysuccinimide ester (OSu) and the amino functionality is acylated with a benzyloxycarbonyl (Z, Cbz) protecting group. The molecule bears a Z-protected amide/urethane-type nitrogen and a carboxyl group masked as the succinimide ester, providing an electrophilic carbonyl that can undergo acyl transfer while the Z group controls chemoselectivity by reducing undesired reactions at the amino site. Z-Sar-OSu is used in peptide coupling and related synthesis as an activated carboxylate equivalent, enabling formation of amide bonds with nucleophiles under conditions where succinimide ester activation is appropriate, and it can also serve as a defined intermediate for preparing further amino acid and peptide derivatives.
CAT No: CP25882
CAS No:53733-96-3
Synonyms/Alias:Z-Sar-OSu;53733-96-3;2,5-dioxopyrrolidin-1-yl2-{[(benzyloxy)carbonyl](methyl)amino}acetate;AmbotzZAA1261;SCHEMBL7285217;CTK8G3899;MolPort-008-269-467;ZINC2526272;7675AB;AKOS016003032;AK-81340;AM025243;HE020547;KB-281500;FT-0698547;K-9715;3B3-062471;2,5-Dioxo-1-pyrrolidinylN-[(benzyloxy)carbonyl]-N-methylglycinate
Chemical Name:N-alpha-Benzyloxycarbonyl-sarcosine succinimidyl ester, N-alpha-Benzyloxycarbonyl-N-alpha-Methyl-glycine succinimidyl ester
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