2-Furoyl-LIGRLO-amide

Name: 2-Furoyl-LIGRLO-amide
Brand: Creative Peptides
SKU: R1835
Availability: MadeToOrder

2-Furoyl-LIGRLO-amide is a potent, selective protease-activated receptor 2 (PAR2) agonist where PAR-2 activation is associated with increases in cAMP and intracellular Ca(2+). Immunoblot analysis revealed, increases in phosphorylation of epidermal growth factor (EGF) receptor (EGFR) tyrosine kinase, Src, Pyk2, cRaf, and ERK1/2 in response to PAR-2 activation.

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CAT No: R1835

CAS No: 729589-58-6

Synonyms/Alias: 2-furoyl-LIGRLO-amide;729589-58-6;2-(2-Furoyl)-leu-ile-gly-arg-leu-orn-nh2;CHEMBL509819;N-[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,5-diamino-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]furan-2-carboxamide;fur-2-oyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2;GLXC-25026;HY-P1314;BDBM50412718;AKOS024457384;MS-31409;PD019049;CS-0029361;G13493;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C36H63N11O8
M.W/Mr.	778
Sequence	One Letter Code:LIGRLX Three Letter Code:fur-2-oyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2
Purity	> 95%

Long-term Storage Conditions	Soluble to 1 mg/ml in water
Shipping Condition	Room temperature
InChI	InChI=1S/C36H63N11O8/c1-7-22(6)29(47-33(52)26(18-21(4)5)46-34(53)27-13-10-16-55-27)35(54)42-19-28(48)43-24(12-9-15-41-36(39)40)31(50)45-25(17-20(2)3)32(51)44-23(30(38)49)11-8-14-37/h10,13,16,20-26,29H,7-9,11-12,14-15,17-19,37H2,1-6H3,(H2,38,49)(H,42,54)(H,43,48)(H,44,51)(H,45,50)(H,46,53)(H,47,52)(H4,39,40,41)/t22-,23-,24-,25-,26-,29-/m0/s1
InChI Key	OSKIRYSKGDEIOG-WTWMNNMUSA-N
Canonical SMILES	CCC(C)C(C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)NC(CC(C)C)C(=O)NC(CCCN)C(=O)N)NC(=O)C(CC(C)C)NC(=O)C1=CC=CO1
Isomeric SMILES	CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)C1=CC=CO1

1. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

2. P-selectin and Complement’s Role in a Neonatal Model of Germinal Matrix Hemorrhage-Induced Secondary Injury

3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

4. Effect of Short-Term Desiccation, Recovery Time, and CAPA-PVK Neuropeptide on the Immune System of the Burying Beetle Nicrophorus vespilloides

5. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency

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