2-Furoyl-LIGRLO-amide

2-Furoyl-LIGRLO-amide is a potent, selective protease-activated receptor 2 (PAR2) agonist where PAR-2 activation is associated with increases in cAMP and intracellular Ca(2+). Immunoblot analysis revealed, increases in phosphorylation of epidermal growth factor (EGF) receptor (EGFR) tyrosine kinase, Src, Pyk2, cRaf, and ERK1/2 in response to PAR-2 activation.

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CAT#R1835
CAS729589-58-6
Synonyms/Alias2-Furoyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2 trifluoroacetate salt; 2-fAP; 2-Fly
M.F/FormulaC36H63N11O8
M.W/Mr.778
SequenceOne Letter Code: LIGRLX (Modifications: Leu-1 = 2-Furoyl-Leu, X = Orn & C-terminal amide)   
Three Letter Code: Fur-2-oyl-Leu-Ile-Gly-Arg-Leu-Orn-NH2
Purity> 95%
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