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  5. 390 MMP FRET Substrate IV

390 MMP FRET Substrate IV

This substrate is readily hydrolyzed by MMP-8, 9 and collagenase-3 (MMP-13), Abs/Em = 325/393 nm. The hydrolysis is inhibited in a 1:1 stoichiometric fashion by the tissue inhibitors of metalloproteinases, TIMP-1, TIMP-2, and TIMP-3.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21164

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.W/Mr.
1100.2
Sequence
One Letter Code: Mca-P-Cha-G-Nva-HA-Dap(Dnp)-NH2
Three Letter Code: Mca-Pro-Cha-Gly-Nva-His-Ala-Dap(Dnp)-NH2
References
1. Lauer-Fields, JL. and GB. Fields, Biol. Chem. 383, 1095 (2002);
2. Lauer-Fields, JL. et al. Biochem. 40, 5795 (2001);
3. Knauper, V. et al. J. Biol. Chem. 271, 1544 (1996).

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